Results 251 to 260 of about 641,617 (352)

Volume kinetics in a translational porcine model of stabilized sepsis with fluid accumulation. [PDF]

Crit Care
Hong SL, Dumargne H, Hahn RG, Hammed A, Lac R, Guilpin A, Slek C, Gerome M, Allaouchiche B, Louzier V, Dargent A.   +10 more
europepmc   +1 more source

Machine Learning‐Enabled Drug‐Induced Toxicity Prediction

Advanced Science, EarlyView.
Unexpected toxicity accounts for 30% of drug development failures. This review highlights ML innovations in predicting drug‐induced toxicity, emphasizing comparative analyses, interpretable algorithms, and multi‐source data integration. It categorizes toxicity types, summarizes ML models, and organizes key databases, offering strategies to address ...
Changsen Bai, Lianlian Wu, Ruijiang Li, Yang Cao, Song He, Xiaochen Bo   +5 more
wiley   +1 more source

Usage of double injector for efficient mixing of the fuel behind the ramp injector at supersonic combustion chamber. [PDF]

Sci Rep
Omar I, El-Sharkawy MR, Ali R, Singh PK, Rajab H, Ahmed M, Ali NB, Rajhi W, Said LB, Abodollahi SA.   +9 more
europepmc   +1 more source

Psychedelic Drugs in Mental Disorders: Current Clinical Scope and Deep Learning‐Based Advanced Perspectives

Advanced Science, EarlyView.
Graphic illustration showing the strategic approaches based on the currently investigated evidence of psychedelics that suggests the challenges and how to address the prescription of mental disorders. These applicable avenues may provide substantial insight into distinguishing between brain networks and psychedelics.
Sung‐Hyun Kim, Sumin Yang, Jeehye Jung, Jeonghyeon Choi, Mingon Kang, Jae‐Yeol Joo   +5 more
wiley   +1 more source

Pediatric Cardiovascular Multiscale Modeling using a Functional Mock-up Interface. [PDF]

Cardiovasc Eng Technol
Garven EE, Kung E, Stevens RM, Throckmorton AL.   +3 more
europepmc   +1 more source

Efficient and Specific PDGFRβ‐Targeting Dual‐Mode T1‐T2 MRI Nanoprobe for Early Diagnosis of Non‐Alcoholic Fatty Liver

Advanced Science, EarlyView.
The Fe3O4/Gd@BSA‐pPB nanoprobe leverages biomimetic mineralization and targets hepatic stellate cells (HSCs) through PDGFRβ, offering superior enrichment in fibrotic regions. This targeted delivery overcomes biological barriers, enhancing both the accuracy and sensitivity of MRI imaging at early disease stages.
Zehua Li, Tongwei Zhang, Tongxiang Tao, Yaxuan Liu, Haining Xia, Sajid ur Rehman, Zeyong Guo, Jing Zhang, Ruiguo Chen, Zhan Zhang, Junfeng Wang, Kun Ma   +11 more
wiley   +1 more source

Glymphatic system: a self-purification circulation in brain. [PDF]

Front Cell Neurosci
Chen S, Wang H, Zhang L, Xi Y, Lu Y, Yu K, Zhu Y, Regina I, Bi Y, Tong F.   +9 more
europepmc   +1 more source

A CLDN18.2‐Targeted Nanoplatform Manipulates Magnetic Hyperthermia Spatiotemporally for Synergistic Immunotherapy in Gastric Cancer

Advanced Science, EarlyView.
CLDN18.2 is a highly selective biomarker exposed in gastric cancer. A CLDN18.2‐specific antibody 1D5 conjugated fluorescence‐magnetic nanoparticle is developed for image‐guided precision theragnostics. Under the assistance of sensitive FMI and deep‐penetrating MPI for tracing and timing the optimal nanoparticle dosage, combining α‐PD1 therapy with ...
Xueying Wang, Hui Hui, Jing Han, Ting Guo, Yiding Wang, Lin Meng, Cong Chen, Jie He, Xiaoyong Guo, Fuyu Zhong, Hong Du, Jie Tian, Xiaofang Xing, Yang Du, Jiafu Ji   +14 more
wiley   +1 more source

Parameter selection and optimization of a computational network model of blood flow in single-ventricle patients. [PDF]

J R Soc Interface
Taylor-LaPole AM, Paun LM, Lior D, Weigand JD, Puelz C, Olufsen MS.   +5 more
europepmc   +1 more source