Results 261 to 270 of about 641,617 (352)

Linking Metastatic Behavior and Metabolic Heterogeneity of Circulating Tumor Cells at Single‐Cell Level Using an Integrative Microfluidic System

open access: yesAdvanced Science, EarlyView.
An integrative workflow is developed to investigate the underlying associations between the metastasis behavior and metabolic characteristics of circulating tumor cells, through tracking the metastatic process on microfluidic chips and combining with mass spectrometry for single‐cell profiling. The bioinformatics analysis uncovers the related metabolic
Ying Hou   +5 more
wiley   +1 more source

Validation of the efficacy of the porous medium model in hemodynamic analysis of iliac vein compression syndrome. [PDF]

open access: yesFront Bioeng Biotechnol
Wei L   +10 more
europepmc   +1 more source

Confinement by Liquid‐Liquid Interface Replicates In Vivo Neutrophil Deformations and Elicits Bleb‐Based Migration

open access: yesAdvanced Science, EarlyView.
Leukocytes sense mechanical cues provided by surrounding cells to regulate motility. Replicating the confining pressures applied by soft, elastic tissues in vitro is challenging. Here, the use of liquid‐liquid interfaces is introduced to model forces exerted by surrounding cells. Confining pressures are tunable by controlling interfacial curvature, and
Jonathan H. Schrope   +13 more
wiley   +1 more source

Label‐Free Dual‐Modal Photoacoustic/Ultrasound Localization Imaging for Studying Acute Kidney Injury

open access: yesAdvanced Science, EarlyView.
This work develops a 3D label‐free photoacoustic/super‐resolution ultrasound imaging system as a comprehensive non‐invasive tool for acute kidney injury (AKI) study. This technique visualizes the intricate structure of renal microvessels and provides critical physiological insights, including renal hemodynamics and oxygenation.
Shensheng Zhao   +5 more
wiley   +1 more source

Dual‐Gating Strategy: Ultrasound Activation of TRPV2 Channels and Borate‐Glass‐Induced Calcium Overload for Tumor Suppression

open access: yesAdvanced Science, EarlyView.
A novel strategy combining borate glass and ultrasound is proposed for the precise treatment of breast cancer. The locally delivered borate glass releases Ca2⁺ ions in situ, while ultrasound activates the highly expressed transient receptor potential vanilloid 2 channels in breast cancer cells. This synergistic effect induces specific calcium overload,
Haihong Zhu   +10 more
wiley   +1 more source

A Hollow Shell‐Lattice Soft Robot in Flexible Pipelines with Flowing Fluids

open access: yesAdvanced Science, EarlyView.
This study proposes a novel shell‐lattice robot with hollow bodies, capable of crawling through pipes with flowing fluids of high velocities and viscosities and mixed with impurities. The robot also features capabilities of crawling with high payloads, in curved pipes, and unthethered crawling. These unique properties make this robot high promising for
Di Guo, Yiqiang Wang, Zhan Kang
wiley   +1 more source

Metabolomic and Cellular Mechanisms of Drug‐Induced Ototoxicity and Nephrotoxicity: Therapeutic Implications of Uric Acid Modulation

open access: yesAdvanced Science, EarlyView.
Drug‐induced renal damage impairs uric acid excretion, causing its accumulation in the serum, which subsequently infiltrates the cochlea. Xanthine oxidase and the ABCG2 transporter, critical in uric acid metabolism and excretion, undergo pathological changes in renal tubular and cochlear stria vascularis cells.
Suhan Guo   +11 more
wiley   +1 more source

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