Results 201 to 210 of about 99,064 (327)

Navigating adverse immunostimulation: A practical guide for clinical researchers

British Journal of Clinical Pharmacology, EarlyView.
Problem Setting As drug development moves towards more complex products, early clinical development programmes are increasingly hampered by unwanted and/or unexpected activation of the immune system (adverse immune stimulation, AIS). Solution At the Centre for Human Drug Research, we have introduced standardized procedures to make AIS manageable, while
Juliette A. van den Noort, Anouk C. Meijs, Naomi B. Klarenbeek, Matthijs Moerland   +3 more
wiley   +1 more source

CARDIOGENIC SHOCK DURING DELIVERY: A TWO-DECADE ANALYSIS OF TRENDS IN INCIDENCE, MORTALITY, AND MECHANICAL CIRCULATORY SUPPORT

Laith Alhuneafat, Fares Ghanem, Carol Pengshung, Ahmad Jabri, Jessica Schultz, Rebecca Cogswell, Andrea Elliott, Abdul Moiz Hafiz, Bhavadharini Ramu   +8 more
openalex   +1 more source

The evolving therapeutic landscape of spinal muscular atrophy – A scoping review of investigational agents, emerging delivery technologies and strategic innovations

British Journal of Clinical Pharmacology, EarlyView.
Spinal muscular atrophy (SMA) is a severe neuromuscular disease with emerging therapeutic complexity. This review aims to systematically map the global pipeline of investigational treatments for SMA. Using ClinicalTrials.gov and complementary international registries, we identified 21 planned or ongoing interventional trials from 2020 to 2025 targeting
Andrej Belančić, Patrick Eustaquio, Elvira Meni Maria Gkrinia, Ivana Stević, Eugen Javor, Yun Wah Lam, Slobodan Janković, Dinko Vitezić   +7 more
wiley   +1 more source

Gordon Wilson Lectures: Shock or Peripheral Circulatory Failure.

, 1941
Alfred Blalock
openalex  

Effects of the endothelin receptor antagonist, SB 209670, on circulatory failure and organ injury in endotoxic shock in the anaesthetized rat

, 1996
Hartmut Ruetten, Christoph Thiemermann, J. R. Vane   +2 more
openalex   +1 more source

Digital diagnostics, biomarkers and therapeutics in an evolving healthcare system: From promise to practice

British Journal of Clinical Pharmacology, EarlyView.
Abstract Health care is shifting towards a digital‐guided system, integrating digital diagnostics, biomarkers and therapeutics in many care pathways. However, despite rapid technological advancement and preliminary adoption accelerated by the COVID‐19 pandemic, a significant implementation gap persists. This narrative review explores the causes of this
Mees H. P. Stoop, Gertjan J. A. Driessen, Adam F. Cohen, Matthijs D. Kruizinga   +3 more
wiley   +1 more source

Fluid Balance and Management and the Critically Ill Woman [PDF]

, 2007
Rowe, N.
core  

Exploring personality traits and mental toughness in early career teachers in England

British Educational Research Journal, EarlyView.
Abstract While some teachers thrive, in similar circumstances other teachers encounter considerable difficulties. This is particularly concerning in England, where high numbers of teachers with five or fewer years' experience leave the profession to take another job outside of teaching, and pupil numbers are outpacing teacher numbers (Bryan & Price ...
Joanne E. Taberner, Sarah MacQuarrie
wiley   +1 more source

Leveraging Hypotension Prediction Index to Forecast LPS-Induced Acute Lung Injury and Inflammation in a Porcine Model: Exploring the Role of Hypoxia-Inducible Factor in Circulatory Shock. [PDF]

Biomedicines
Tsai YM, Lin YC, Chen CY, Chien HC, Chang H, Chiang MH.   +5 more
europepmc   +1 more source

Measuring what matters: Evaluating the impact of curriculum decolonisation initiatives in UK business schools

British Educational Research Journal, EarlyView.
Abstract Curriculum decolonisation has become a prominent feature of equity agendas in UK higher education, yet there remains limited empirical and theoretical work on how such initiatives are evaluated, particularly within business schools. This paper presents one of the first multi‐institutional empirical studies examining how UK business schools ...
Sally Everett, Rachael Carden, Kenisha Linton   +2 more
wiley   +1 more source