Results 91 to 100 of about 966,353 (288)

Peripheral blood leukocyte signatures as biomarkers in relapsed ovarian cancer patients receiving combined anti‐CD73/anti‐PD‐L1 immunotherapy in arm A of the NSGO‐OV‐UMB1/ENGOT‐OV30 trial

open access: yesMolecular Oncology, EarlyView.
Using mass cytometry, we analyzed serial blood samples from patients with relapsed epithelial ovarian cancer (EOC) treated with oleclumab–durvalumab combination immunotherapy in the NSGO‐OV‐UMB1/ENGOT‐OV30 trial. Our analysis identified potential predictive, monitoring, and response biomarkers detectable through liquid biopsy. These findings facilitate
Luka Tandaric   +11 more
wiley   +1 more source

Influence of the state of the local system of nonspecific protection the oral fluid on clinical periodontal status indicators

open access: yesКубанский научный медицинский вестник, 2015
The relationship of periodontal disease and somatic pathology determines the interest of the dentist to the peculiarities of the local organization of nonspecific protection and the search for new ways of non-invasive diagnosis and monitoring for ...
V. A. Akopova   +4 more
doaj  

Biomarkers That Seem to Have the Greatest Impact on Promoting the Formation of Atherosclerotic Plaque in Current Scientific Research

open access: yesCurrent Issues in Molecular Biology
Atherosclerosis is a chronic inflammatory disease that causes degenerative and productive changes in the arteries. The resulting atherosclerotic plaques restrict the vessel lumen, causing blood flow disturbances.
Maksymilian Kłosowicz   +5 more
doaj   +1 more source

Forecasting Leading Death Causes in Australia using Extended CreditRisk$+$ [PDF]

open access: yesarXiv, 2015
Recently we developed a new framework in Hirz et al (2015) to model stochastic mortality using extended CreditRisk$^+$ methodology which is very different from traditional time series methods used for mortality modelling previously. In this framework, deaths are driven by common latent stochastic risk factors which may be interpreted as death causes ...
arxiv  

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

open access: yesMolecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park   +6 more
wiley   +1 more source

Molecular Communication-Inspired Particle Collector-Transmitter (PaCoT) for Heavy Metal Removal from Human Circulatory System [PDF]

open access: yesarXiv
This study proposes a novel molecular communication (MC)-inspired nanomachine, PArticle COllector-Transmitter (PaCoT), to remove toxic heavy metals from the human circulatory system. PaCoT collects these toxic metals and transmits them to release nodes, such as lymph capillaries, before they reach critical organs.
arxiv  

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