Results 41 to 50 of about 22,286,613 (347)
Nitric oxide (NO) produced in the wall of blood vessels is necessary for the regulation of vascular tone to ensure an adequate blood supply of organs and tissues.
D. Gaynullina, R. Schubert, O. Tarasova
semanticscholar +1 more source
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac+3 more
wiley +1 more source
The silent pandemic in South Africa: Extra-pulmonary tuberculosis from head to heel
Extra-pulmonary tuberculosis (EPTB), caused by Mycobacterium tuberculosis, is the leading cause of communicable disease-related deaths in people with human immunodeficiency virus (HIV) worldwide and in South Africa.
Camilla E. Le Roux, Sucari S.C. Vlok
doaj +1 more source
Critical Thinking Skills (CTSs) are fundamental skills possessed by students to adapt to the external challenges of 21st-century. To empower students’ CTSs, Guided Inquiry and INSTAD may work effectively.
B. K. B. Putra, B. Prayitno, M. Maridi
semanticscholar +1 more source
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi+3 more
wiley +1 more source
Virtual laboratory for simulation and learning of cardiovascular system function in BME studies
The application of engineering system analysis is a very important field in biomedical engineering (BME) studies: modeling, simulation and control of the most important physiological systems.
Alher Mauricio Hernández Valdivieso+4 more
doaj +1 more source
HOTS assessment in circulatory system learning: Validity, reliability, and item quality
Biology learning, based on the curriculum-2013, requires students to be skilled at analyzing, evaluating, and creating to achieve Higher-Order Thinking Skills (HOTS). Thus, HOTS assessment instrument is crucial to be made.
Yosi Laila Rahmi+3 more
doaj +1 more source
Pregnancy and the circulatory system [PDF]
n ...
openaire +3 more sources
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source