Results 81 to 90 of about 22,286,613 (347)

Massively parallel models of the human circulatory system

International Conference for High Performance Computing, Networking, Storage and Analysis, 2015
The potential impact of blood flow simulations on the diagnosis and treatment of patients suffering from vascular disease is tremendous. Empowering models of the full arterial tree can provide insight into diseases such as arterial hypertension and ...
A. Randles, E. Draeger, T. Oppelstrup, L. Krauss, John A. Gunnels   +4 more
semanticscholar   +1 more source

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

Molecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma, Sophia M. Orbach, Kate V. Griffin, Kathryn Kang, Yining Zhang, Rebecca S. Pereles, Ian A. Schrack, Guillermo Escalona, Jacqueline S. Jeruss, Lonnie D. Shea   +9 more
wiley   +1 more source

Outcomes related to hospital characteristics of heart transplant centers: A National Readmission Database analysis

JHLT Open
Background: This study showcases an analysis performed using the National Readmission Database (NRD) from 2016 to 2019 to analyze the impact of ownership, location, size, and teaching status of transplant centers on cardiac transplant outcomes.
Farshad Amirkhosravi, MD, MPH, Duc T. Nguyen, MD, PhD, Roberto Secchi Del Rio, MD, Edward A. Graviss, PhD, MPH, Nadia Fida, MD, Ashrith Guha, MD, MPH, Cindy Martin, MD, Eric Suarez, MD, Lin-Chiang Philip Chou, MD, Arvind Bhimaraj, MD, MPH   +9 more
doaj  

Peculiarities of adaptation reactions in female migrants and health disorders risks occuring after different periods of staying on Moscow region territory

Analiz Riska Zdorovʹû, 2017
The article gives the results of determining peculiarities which are characteristic for adaptation in female migrants de-pending on a period of their staying in Moscow region.
N.F. Izmerov, N.I. Izmerova, I.V. Bukhtiyarov, M. Khodzhiev   +3 more
doaj   +1 more source

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

Molecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton, Russell W. Madison, Candice Francheska B. Tambaoan, Funda Meric‐Bernstam, Christopher J. Sweeney, Razelle Kurzrock, Howard A. Burris III, David R. Spigel, Hanna Tukachinsky, Jason Hughes, Julia Malato, Bongin Yoo, Tania Szado, Cheryl Schwab, Lincoln W. Pasquina, Amaya Gasco, Katja Schulze, Claire F. Friedman   +17 more
wiley   +1 more source

THE ENERGY INDEX OF THE CIRCULATORY SYSTEM [PDF]

The American Journal of the Medical Sciences, 1916
n ...
openaire   +2 more sources

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

Molecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Study of dispensary patients of working age with circulatory system diseases through the automated control systems

SHS Web of Conferences, 2018
Diseases of the circulatory system occupy a leading position among the diseases prevalence of which is increasing with each passing year and is sustainable.
Abdikadirova I., Chukmaitov A.S., Yermukhanova L., Bekbauova A.   +3 more
doaj   +1 more source

Health effects of exposure to static magnetic field − a review of literature

Medycyna Pracy, 2019
The authors discuss the effects of static magnetic field (SMF) exposure based on reviewed literature reports. The systematic review covered both research carried out directly with people as well as studies with animals.
Marek Zmyślony, Piotr Politański
doaj   +1 more source

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

Molecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach, Nilesh Chatterjee, Kellie Spahr, Gilberto Serrano de Almeida, Anabel Varela‐Carver, Taimur T. Shah, Mathias Winkler, Hashim U. Ahmed, Charlotte L. Bevan   +8 more
wiley   +1 more source