Results 131 to 140 of about 419,003 (365)
TGF-β1 Induces the Dual Regulation of Hepatic Progenitor Cells with Both Anti- and Proliver Fibrosis
Stem Cells International, 2016 Transforming growth factor-beta 1 (TGF-β1) plays a central role in hepatic progenitor cells- (HPCs-) mediated liver repair and fibrosis. However, different effects of TGF-β1 on progenitor cells have not been described.
Ai-Ting Yang +9 more
doaj +1 more source
On estimation in varying coefficient models for sparse and irregularly sampled functional data [PDF]
arXiv, 2017 In this paper, we study a smoothness regularization method for a varying coefficient model based on sparse and irregularly sampled functional data which is contaminated with some measurement errors. We estimate the one-dimensional covariance and cross-covariance functions of the underlying stochastic processes based on a reproducing kernel Hilbert ...
arxiv
The efficacy of choline as an adjuvant in the therapy of Laennec's cirrhosis [PDF]
, 1951 Thesis (M.D.)—Boston ...
Bednarz, Wallace
core
Advanced Science, EarlyView.Using the MOSTtechnology and whole‐liver Nissl staining method, a multi‐structural 3D pathological panorama of liver fibrosis is obtained. The damaged sinusoids, steatotic hepatocytes, and collagen deposition are all concentrated in pericentral areas.
Xiaochuan Zhang +13 more
wiley +1 more source
JHEP Reports, 2022 Background & Aims: Acute-on-chronic liver failure (ACLF) is a syndrome associated with organ failure and high short-term mortality. Recently, the role of surgery as a precipitating event for ACLF has been characterised.
Johannes Chang +12 more
doaj
A Bayesian Approach to Modelling Longitudinal Data in Electronic Health Records [PDF]
arXiv, 2019 Analyzing electronic health records (EHR) poses significant challenges because often few samples are available describing a patient's health and, when available, their information content is highly diverse. The problem we consider is how to integrate sparsely sampled longitudinal data, missing measurements informative of the underlying health status ...
arxiv
Sarcopenia in cirrhosis: from pathogenesis to interventions
Journal of gastroenterology, 2019 Sarcopenia (severe muscle depletion) is a prevalent muscle abnormality in patients with cirrhosis that confers poor prognosis both pre- and post-liver transplantation. The pathogenesis of sarcopenia is multifactorial and results from an imbalance between
M. Ebadi +3 more
semanticscholar +1 more source
Gastroenterology, 2020 BACKGROUND & AIMS Cirrhosis is associated with changes in gut microbiome composition. Although ACLF is the most severe clinical stage of cirrhosis, there is lack of information about gut microbiome alterations in ACLF using quantitative metagenomics.
C. Solé +22 more
semanticscholar +1 more source
Comparison of Clinical Scores for Predicting Stroke‐Associated Pneumonia After Acute Ischemic Stroke
AGING MEDICINE, EarlyView.Our study compared the discrimination and calibration of the Kwon Pneumonia Score, A2DS2 score, PANTHERIS score, AIS‐APS score, ISAN score, and PASS score in SAP identification; of these, the AIS‐APS score showed the best performance. ABSTRACT Objectives To compare the discrimination and calibration of six risk scoring systems in the assessment of ...
Linlin Wang +8 more
wiley +1 more source
Ledipasvir and sofosbuvir for 8 or 12 weeks for chronic HCV without cirrhosis.
New England Journal of Medicine, 2014 BACKGROUND High rates of sustained virologic response were observed among patients with hepatitis C virus (HCV) infection who received 12 weeks of treatment with the nucleotide polymerase inhibitor sofosbuvir combined with the NS5A inhibitor ledipasvir ...
K. Kowdley +24 more
semanticscholar +1 more source