Results 131 to 140 of about 651,238 (350)
Immunoreactive human chorionic gonadotropin and its free ß-subunit in serum and ascites of patients with malignant tumors [PDF]
, 1992 Human chorionic gonadotropin (hCG) is a clinically relevant marker of trophoblastic and nontrophoblastic malignancies. In the present studies, in addition to determining serum hCG, we investigated the presence and properties of hCG immunoreactivity in ...Gerbes, Alexander L., Hörmann, Rudolf, Jüngst, Dieter, Mann, Klaus, Spöttl, Gerald +4 morecore Association of HAMP Expression and CD8+ T‐Cell Infiltration With Atezolizumab–Bevacizumab Response in Hepatocellular Carcinoma
Annals of Gastroenterological Surgery, EarlyView.In hepatocellular carcinoma treated with atezolizumab–bevacizumab, responders showed RNA‐seq enrichment of immune and chemokine pathways with higher HAMP expression. In resected specimens, immunohistochemistry confirmed increased intratumoral CD8+ T‐cell density and hepcidin (HAMP), supporting HAMP plus CD8 as components of a composite predictor of ...Shun Nakamura, Yuki Murakami, Yusuke Oshima, Takashi Masuda, Wataru Miyoshino, Hiroomi Takayama, Yoko Kawano, Teijiro Hirashita, Yuichi Endo, Masafumi Inomata +9 morewiley +1 more sourceIntestinal peroxisome proliferator‐activated receptor α‐fatty acid‐binding protein 1 axis modulates nonalcoholic steatohepatitis
Hepatology, EarlyView., 2022 Abstract Background and Aims
Peroxisome proliferator‐activated receptor α (PPARα) regulates fatty acid transport and catabolism in liver. However, the role of intestinal PPARα in lipid homeostasis is largely unknown. Here, intestinal PPARα was examined for its modulation of obesity and NASH. Approach and Results
Intestinal PPARα was activated and fatty Tingting Yan, Yuhong Luo, Nana Yan, Keisuke Hamada, Nan Zhao, Yangliu Xia, Ping Wang, Changdong Zhao, Dan Qi, Shoumei Yang, Lulu Sun, Jie Cai, Qiong Wang, Changtao Jiang, Oksana Gavrilova, Kristopher W. Krausz, Daxesh P. Patel, Xiaoting Yu, Xuan Wu, Haiping Hao, Weiwei Liu, Aijuan Qu, Frank J. Gonzalez +22 morewiley +1 more sourceSurgical Outcomes and Recurrence Management in Borderline Resectable Hepatocellular Carcinoma: Implications for Multidisciplinary Strategies
Annals of Gastroenterological Surgery, EarlyView.Multivariate analysis identified that up‐to‐7 out (p < 0.001), lymph node metastasis (p < 0.001), and non‐anatomical resection (p = 0.02) were independent predictors of cancer recurrence, while older age (p = 0.01), Child‐Pugh B (p < 0.001), up‐to‐7 out (p = 0.01), macrovascular invasion (p = 0.01), and lymph node metastasis (p < 0.001) were ...Koichiro Haruki, Kenei Furukawa, Munetoshi Akaoka, Yuto Yamahata, Shinji Onda, Yoshihiro Shirai, Masashi Tsunematsu, Tomohiko Taniai, Michinori Matsumoto, Toru Ikegami +9 morewiley +1 more sourceNAFLD‐related hepatocellular carcinoma: The growing challenge
Hepatology, EarlyView., 2022 Risk and protective factors for NAFLD‐related hepatocellular carcinoma Abstract
Hepatocellular carcinoma (HCC) is a common cause of cancer‐related mortality and morbidity worldwide. With the obesity pandemic, NAFLD‐related HCC is contributing to the burden of disease exponentially.Pir Ahmad Shah, Rashmee Patil, Stephen A. Harrison +2 morewiley +1 more sourceCost-effectiveness of non-invasive methods for assessment and monitoring of liver fibrosis and cirrhosis in patients with chronic liver disease: systematic review and economic evaluation [PDF]
, 2015 BACKGROUND: Liver biopsy is the reference standard for diagnosing the extent of fibrosis in chronic liver disease; however, it is invasive, with the potential for serious complications., , , , , , , , , , , , , , , , , , , , , , , Adams, Adams, Afdhal, Aguirre, Ahmad, Aithal, Al-Mohri, Anaparthy, Andersson, Angulo, Arena, Argo, Asbach, Ascher, Aube, Aube, Awaya, Barshop, Barton, Bataller, Beckebaum, Bedossa, Bejarano, Belfort, Bellentani, Ben Jazia, Bennett, Berg, Blomme, Bolondi, Bonkovsky, Boring, Borroni, Bourliere, Boursier, Boursier, Briggs, Brown, Brunetto, Buntinx, Burton, Cales, Cales, Cales, Calvaruso, Calvaruso, Calvaruso, Camma, Cardi, Cardoso, Carlson, Carrion, Carvalho-Filho, Castera, Castera, Castera, Castera, Castera, Castera, Ceriani, Chalasani, Chalasani, Chan, Chang, Chavez-Tapia, Cheinquer, Chen, Chen, Chen, Cheung, Cho, Cholongitas, Chong, Chou, Christensen, Chrysanthos, Cioni, Claxton, Cobbold, Colletta, Colli, Colli, Colombo, Corradi, Crespo, Cross, Crowley, Crowley, Curtis, da Silva, Dakin, Danila, David, Davis, de Franchis, De Freitas, De Jongh, de Ledinghen, De Ledinghen, Degos, Denzer, Detre, Di Bisceglie, Di Marco, Dinesen, Dixon, Dixon, Do, Donnan, Drummond, Dusheiko, D’Amico, D’Onofrio, Ekstedt, Esmat, Esteban, Fabris, Fahmy, Fattovich, Fattovich, Fattovich, Fattovich, Fattovich, Fattovich, Feldstein, Fenwick, Ferral, Fontaine, Fontana, Fontanges, Forestier, Forns, Fraquelli, Fried, Fried, Friedrich-Rust, Fujii, Fujimoto, Fung, Gaia, Gaia, Gaiani, Ganne-Carrie, Gara, Germani, Germani, Giannini, Gierblinski, Gobel, Goodman, Goyal, Grieve, Grishchenko, Guajardo-Salinas, Guechot, Guechot, Guha, Gui, Guo-Qiu, Guzelbulut, Hadziyannis, Halfon, Halfon, Halfon, Hall, Harada, Harrison, Haukeland, Hongbo, Hoofnagle, Hsieh, Hu, Huang, Hui, Huwart, Iacobellis, Ibrahim, Idilman, Imbert-Bismut, Imperiale, Isgro, Ishibashi, Islam, Iushchuk, Jacobson, Jacobson, Jacobson, Janssens, John-Baptiste, Jones, Jones, Joseph, Kalantari, Kamal, Kamphues, Kandemir, Kaneda, Kayadibi, Kelleher, Kelleher, Khan, Khosravi, Kilpe, Kim, Kim, Kim, Kim, Kim, Kim, Kim, Kim, Koda, Koizumi, Kwok, Lackner, Ladenheim, Ladero, Lai, Lampertico, Lau, Lavallard, Lavanchy, Lavine, Lawitz, Lee, Lee, Lee, Leroy, Leroy, Leroy, Lesmana, Levy, Lewin, Li, Liaw, Liaw, Lichtinghagen, Lieber, Lin, Liu, Liu, Liu, Liu, Liu, Liu, Loko, Longworth, Lupsor, Lupsor, Lupsor, Lutz, Lydatakis, Macaskill, Macias, Macias, Mahadeva, Mahady, Mahady, Mallet, Manns, Manns, Manousou, Manousou, Marcellin, Marcellin, Marcellin, Martinez, Martinez, McLernon, McPherson, McPherson, Melin, Miailhes, Mohamadnejad, Moreno-Otero, Morgan, Morikawa, Motosugi, Mueller, Mummadi, Murawaki, Musso, Myers, Myers, Nagata, Nahon, Naveau, Naveau, Nguyen-Khac, Nishiura, Nitta, Nojiri, Numminen, Nunes, Obara, Ogawa, Oliveira, Ong, Orlacchio, Orlacchio, Osakabe, O’Shea, Paggi, Pais, Palmeri, Papalavrentios, Parise, Park, Park, Park, Park, Park, Parkes, Patel, Patel, Pawitpok, Pereira, Petta, Pimentel, Pohl, Poordad, Poynard, Poynard, Poynard, Poynard, Prati, Promrat, Qian, Qiu, Qureshi, Raftopoulos, Rakoski, Ramachandran, Raszeja-Wyszomirska, Ratziu, Ratziu, Ratziu, Ratziua, Realdi, Reedy, Reitsma, Ronot, Rosenberg, Rossi, Rossini, Ruffillo, Rustogi, Saab, Said, Saitou, Sakugawa, Sancheztapias, Sandrasegaran, Santos, Sanvisens, Sanyal, Sanyal, Sanyal, Schiavon, Schiavon, Schneider, Schneider, Schuetz, Sebastian, Sebastiani, Sebastiani, Sebastiani, Sebastiani, Sene, Seto, Sharabash, Shastry, Shen, Shepherd, Shepherd, Shepherd, Sherman, Sheth, Shields, Shiffman, Shimada, Shin, Shinkins, Shiramizu, Siebert, Sinakos, Singal, Sirli, Snyder, Snyder, Sohn, Sohn, Sokucu, Sonnenberg, Sporea, Sporea, Sporea, Sporea, Sporea, Standish, Sterling, Stevenson, Stibbe, Sud, Sumida, Sumida, Suzuki, Sweeting, Takeda, Tassopoulos, Terjung, Testa, Thompson, Thompson, Thompson, Thompson Coon, Thompson Coon, Tillmann, Tome, Toniutto, Tran, Trang, Trifan, Trocme, Tsochatzis, Tsochatzis, Tsochatzis, Tsochatzis, Tsochatzis, Tural, Uygun, Vallet-Pichard, Valva, Vanbiervliet, Varaut, Veenstra, Veenstra, Venkatesh, Vernon, Verrill, Viana, Vigano, Viganò, Wai, Wang, Wang, Ware, Westin, Whiting, Whiting, Whiting, Whiting, Wilby, Wilck, Wilson, Wong, Wong, Wong, Wong, Wong, Wong, Wong, Wong, Woo, Wright, Wu, Xu, Yoneda, Yoneda, Younossi, Younossi, Yuen, Zaman, Zarski, Zarski, Zhang, Zhang, Zhang, Zhu, Zhu, Ziol +503 morecore +2 more sourcesBona Fide Intersegmental Plane Hepatectomy Along the Glissonean Branches (BIPHG)
Annals of Gastroenterological Surgery, EarlyView.ABSTRACT
This review traces the author's personal journey over three decades in the evolution of liver resection techniques, culminating in the proposal of the Bona Fide Intersegmental Plane Hepatectomy Along Glissonean Branches (BIPHG). Beginning with pioneering experiences in laparoscopic and robotic liver surgeries, the author highlights key ...Go Wakabayashi, Taiga Wakabayashiwiley +1 more sourceLipocalin‐2 activates hepatic stellate cells and promotes nonalcoholic steatohepatitis in high‐fat diet–fed Ob/Ob mice
Hepatology, EarlyView., 2022 Graphical summary of obesity‐induced NASH progression by LCN2 targeted to HSC activation. Abstract Background and Aims
In obesity and type 2 diabetes mellitus, leptin promotes insulin resistance and contributes to the progression of NASH via activation of hepatic stellate cells (HSCs).Kyung Eun Kim, Jaewoong Lee, Hyun Joo Shin, Eun Ae Jeong, Hye Min Jang, Yu Jeong Ahn, Hyeong Seok An, Jong Youl Lee, Meong Cheol Shin, Soo Kyoung Kim, Won Gi Yoo, Won Ho Kim, Gu Seob Roh +12 morewiley +1 more source