Results 151 to 160 of about 419,003 (365)

Liver Cancer: Connections with Obesity, Fatty Liver, and Cirrhosis.

Annual Review of Medicine, 2016
The burden of hepatocellular carcinoma (HCC), the most common form of liver cancer, is steadily growing because obesity, type 2 diabetes, and nonalcoholic fatty liver disease (NAFLD) are replacing viral- and alcohol-related liver disease as major ...
A. Marengo, C. Rosso, E. Bugianesi
semanticscholar   +1 more source

Osteopenic occult vertebral fracture is associated with poor oncological outcome in patients with hepatocellular carcinoma after hepatic resection

Annals of Gastroenterological Surgery, EarlyView.
Osteopenic occult vertebral fracture (OVF) was associated with poor long‐term outcomes in patients with HCC after hepatic resection. Osteopenic OVF had a poorer prognosis than that of patients with either osteopenia or OVF. Abstract Background Although osteopenia has been associated with poor outcomes in patients with hepatocellular carcinoma (HCC ...
Koichiro Haruki, Kenei Furukawa, Munetoshi Akaoka, Masashi Tsunematsu, Michinori Matsumoto, Tomohiko Taniai, Yoshihiro Shirai, Shinji Onda, Ryoga Hamura, Toru Ikegami   +9 more
wiley   +1 more source

Cyclic AMP metabolism and adenylate cyclase concentration in patients with advanced hepatic cirrhosis [PDF]

, 1978
Glucagon was tested for its effect on plasma adenosine 3′,5′-cyclic monophosphate (cyclic AMP), insulin, and glucose in healthy subjects and in patients with advanced cirrhosis of the liver. In the normal subjects, intravenous infusion of glucagon caused
Antonio Francavilla, Arthur F. Jones, Ball, Blonde, Bressler, Broadus, Broadus, Broadus, Brooker, Charles, Cherrington, Claycomb, Conn, Conn, Conn, Davies, Exton, Exton, Felig, Foa, Francavilla, Gilman, Hendy, Jerumo, Kaminsky, Kimmel, Krishna, Lambert, Lambert, Lambert, Levine, Liljenquist, Mackrell, Makman, Marco, McCullough, Milner, Miyamoto, Mori, Robison, Salomon, Sherwin, Srikant, Starzl, Strange, Strange, Sullivan, Sutherland, Taylor, Thomas E. Starzl, Turinsky, Turtle, Unger, Van Itallie, Vecchio, Verhaegen, Wahren, Walsh, White, Williams, Yalow, Zenser   +61 more
core   +1 more source

FIB‐3 index as a novel age‐independent predictor of liver fibrosis and prognosis in hepatocellular carcinoma patients undergoing hepatectomy

Annals of Gastroenterological Surgery, EarlyView.
Fibrosis‐3 index (FIB‐3) can stratify the risk of the survival and the recurrence‐free survival. The FIB‐3 index is a reliable, age‐independent tool for assessing liver fibrosis and prognosis in HCC patients post‐hepatectomy. Its use may improve clinical outcomes and support personalized treatment strategies. Abstract Background Liver fibrosis is a key
Yuki Imaoka, Masahiro Ohira, Tsuyoshi Kobayashi, Naruhiko Honmyo, Michinori Hamaoka, Takashi Onoe, Daisuke Takei, Koichi Oishi, Tomoyuki Abe, Toshihiro Nakayama, Miho Akabane, Kazunari Sasaki, Hideki Ohdan, Hiroshima Surgical study group of Clinical Oncology (HiSCO)   +13 more
wiley   +1 more source

Gut microbiota–derived short‐chain fatty acids regulate group 3 innate lymphoid cells in HCC

Hepatology, EarlyView., 2022
Abstract Background and Aims Type 3 innate lymphoid cells (ILC3s) are essential for host defense against infection and tissue homeostasis. However, their role in the development of HCC has not been adequately confirmed. In this study, we investigated the immunomodulatory role of short‐chain fatty acids (SCFAs) derived from intestinal microbiota in ILC3
Chupeng Hu, Bingqing Xu, Xiaodong Wang, Wen‐Hua Wan, Jinying Lu, Deyuan Kong, Yu Jin, Wenhua You, Hua Sun, Xiaoxin Mu, Dongju Feng, Yun Chen   +11 more
wiley   +1 more source

Elevated serum levels of glial fibrillary acidic protein are associated with covert hepatic encephalopathy in patients with cirrhosis

JHEP Reports, 2023
Background & Aims: Blood biomarkers facilitating the diagnosis of covert hepatic encephalopathy (CHE) in patients with cirrhosis are lacking. Astrocyte swelling is a major component of hepatic encephalopathy.
Simon Johannes Gairing, Sven Danneberg, Leonard Kaps, Michael Nagel, Eva Maria Schleicher, Charlotte Quack, Sinah Engel, Stefan Bittner, Peter Robert Galle, Jörn Markus Schattenberg, Marcus-Alexander Wörns, Felix Luessi, Jens Uwe Marquardt, Christian Labenz   +13 more
doaj  

Environmental Stressors and the Unfolded Protein Response (UPR) in Exocrine Pancreatic Function

Frontiers in Physiology, 2011
The exocrine pancreas has the greatest synthetic capacity of any mammalian organ and as such is challenged with synthesis, processing and transporting a large load of digestive enzymes.
Stephen J Pandol, Stephen J Pandol, Stephen J Pandol, Fred eGorelick, Aurelia eLugea, Aurelia eLugea   +5 more
doaj   +1 more source

Sofosbuvir and Velpatasvir for HCV in Patients with Decompensated Cirrhosis.

New England Journal of Medicine, 2015
BACKGROUND As the population that is infected with the hepatitis C virus (HCV) ages, the number of patients with decompensated cirrhosis is expected to increase.
Michael P. Curry, J. O’Leary, N. Bzowej, A. Muir, K. Korenblat, J. Fenkel, K. Reddy, E. Lawitz, S. Flamm, T. Schiano, L. Teperman, R. Fontana, EugeneR. Schiff, M. Fried, B. Doehle, D. An, J. McNally, A. Osinusi, D. Brainard, J. Mchutchison, Robert S. Brown, Michael Charlton   +21 more
semanticscholar   +1 more source

Near‐Infrared Organic Room Temperature Phosphorescent Probes Targeting Fibroblast Activation Protein for Surgical Navigation of Liver Cancer

Aggregate, EarlyView.
A near‐infrared organic room temperature phosphorescence probe of fibroblast‐activation protein in liver cancer microenvironment is prepared to accurately locate liver cancer and determine surgical margins, aiming at guiding hepatectomy and achieving accurate liver cancer resection.
Jinghua Li, Juqing Gu, Liangxuan Ding, Xiaomian Li, Peng Xia, Fusheng Liu, Xi Chen, Weijie Ma, Yong He, Qianqian Li, Zhen Li, Yufeng Yuan   +11 more
wiley   +1 more source

Relationship between NAFLD and coronary artery disease: A Mendelian randomization study

Hepatology, EarlyView., 2022
Abstract Background and Aims There is an ongoing debate on whether NAFLD is an active contributor or an innocent bystander in the pathogenesis of coronary artery disease (CAD). The aim of the present study was to assess the causal relationship between NAFLD and CAD.
Zhewen Ren, Pomme I. H. G. Simons, Anke Wesselius, Coen D. A. Stehouwer, Martijn C. G. J. Brouwers   +4 more
wiley   +1 more source