Results 181 to 190 of about 419,003 (365)

Contemporary management of pain in cirrhosis: Toward precision therapy for pain

open access: yesHepatology, EarlyView., 2022
Abstract Chronic pain is highly prevalent in patients with cirrhosis and is associated with poor health‐related quality of life and poor functional status. However, there is limited guidance on appropriate pain management in this population, and pharmacologic treatment can be harmful, leading to adverse outcomes, such as gastrointestinal bleeding ...
Alexis Holman   +4 more
wiley   +1 more source

Nonlinear association structures in flexible Bayesian additive joint models [PDF]

open access: yesarXiv, 2017
Joint models of longitudinal and survival data have become an important tool for modeling associations between longitudinal biomarkers and event processes. The association between marker and log-hazard is assumed to be linear in existing shared random effects models, with this assumption usually remaining unchecked.
arxiv  

Intrarenal Resistance Index as a Prognostic Parameter in Patients with Liver Cirrhosis Compared with Other Hepatic Scoring Systems [PDF]

open access: yes, 2012
Background and Aims: Patients with advanced liver cirrhosis who develop renal dysfunction have a poor prognosis. Elevated intrarenal resistance indices (RIs) due to renal vascular constriction have been described before in cirrhotic patients.
Bardi A   +14 more
core   +1 more source

Recent advances of nanomaterials in imaging liver fibrosis

open access: yesBMEMat, EarlyView.
Schematic summary on the latest strategies of liver fibrosis imaging based on various nanomaterials. Abstract Liver fibrosis is a pathological process resulting from prolonged exposure to various injury factors. It is characterized by the abnormal proliferation and activation of hepatic stellate cells and excessive deposition of extracellular matrix ...
Jin Cui   +11 more
wiley   +1 more source

IL‐31 levels correlate with pruritus in patients with cholestatic and metabolic liver diseases and is farnesoid X receptor responsive in NASH

open access: yesHepatology, EarlyView., 2022
IL‐31 levels correlate with pruritus in patients with cholestatic and metabolic liver diseases Abstract Background and Aims Pruritus is associated with multiple liver diseases, particularly those with cholestasis, but the mechanism remains incompletely understood.
Jun Xu   +20 more
wiley   +1 more source

Mechanisms of Alcohol-Induced Endoplasmic Reticulum Stress and Organ Injuries

open access: yesBiochemistry Research International, 2012
Alcohol is readily distributed throughout the body in the blood stream and crosses biological membranes, which affect virtually all biological processes inside the cell.
Cheng Ji
doaj   +1 more source

CirrMRI600+: Large Scale MRI Collection and Segmentation of Cirrhotic Liver [PDF]

open access: yesarXiv
Liver cirrhosis, the end stage of chronic liver disease, is characterized by extensive bridging fibrosis and nodular regeneration, leading to an increased risk of liver failure, complications of portal hypertension, malignancy and death. Early diagnosis and management of end-stage cirrhosis are significant clinical challenges.
arxiv  

A Joint Deep Learning Approach for Automated Liver and Tumor Segmentation [PDF]

open access: yesarXiv, 2019
Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer in adults, and the most common cause of death of people suffering from cirrhosis. The segmentation of liver lesions in CT images allows assessment of tumor load, treatment planning, prognosis and monitoring of treatment response.
arxiv  

Liver organoids: From 3D printing to biomedical applications

open access: yesBMEMat, EarlyView.
A comprehensive review on liver organoids culture techniques from 3D printing to organ‐on‐chip, as well as focusing on challenges and perspectives for advancement liver organoids in various future applications. Abstract The liver is an immune organ, especially an immune tolerance organ.
Ying Shi   +4 more
wiley   +1 more source

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