Results 321 to 330 of about 481,695 (368)

Patient‐derived tumor organoids highlight the potential of precision medicine in managing pancreatic ductal adenocarcinoma

International Journal of Cancer, EarlyView.
What's New? Only about one‐fifth of patients with pancreatic ductal adenocarcinoma (PDAC) qualify for curative treatment approaches employing adjuvant chemotherapy. Tools to predict PDAC response to chemotherapeutic regimens, however, are lacking.
Christine Nitschke, Charline Phan, Yara Souto, Philipp Walter, Mara Goetz, Gediminas Simkus, Jacob Thastrup, Ronald Simon, Jürgen Kupper, Jakob Izbicki, Steven A. Johnsen, Thilo Hackert, Marianne Sinn, Harriet Wikman, Faik G. Uzunoglu, Tabea M. Sturmheit   +15 more
wiley   +1 more source

Post COVID Condition and Long-Term COVID-19 Impact on Hepatic Decompensation and Survival in Cirrhosis: A Propensity Matched Observational Study. [PDF]

JGH Open
Sharma P, Premkumar M, Guru RR, Sandhu A, Kajal K, De A, Rathi S, Verma N, Taneja S, Singh V, Duseja AK.   +10 more
europepmc   +1 more source

FIGO guideline on liver disease and pregnancy

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract The number of women entering pregnancy with chronic liver disease is rising. Gestational liver disorders affect 3% of the pregnant population. Both can be associated with significant maternal and fetal morbidity and mortality. European guidance has recently been published to inform management.
Melanie Nana, Virna Medina, Cynthia Maxwell, Ciara McCormick, Gloria Taliani, Ulrich Beuers, Deborah Money, Bo Jacobsson, Anil Kapur, Titus Beyuo, Francisco Ruiloba, Graeme Smith, Lina Bergman, Sharleen O'Reilly, Patrick O'Brien, Mark Hanson, Mary Rosser, Claudio Sosa, Sumaiya Adam, Valerie Guinto, Liona Poon, Fionnuala McAuliffe, Catherine Williamson, on behalf of the FIGO Committee on Impact of Pregnancy on Long‐term Health, FIGO Committee on Infections during Pregnancy and the FIGO Division of Maternal and Newborn Health   +24 more
wiley   +1 more source

The Global Burden of Cirrhosis and Other Chronic Liver Diseases in 2021. [PDF]

Liver Int
Tham EKJ, Tan DJH, Danpanichkul P, Ng CH, Syn N, Koh B, Lim RYZ, Wijarnpreecha K, Teng MLP, Nah BKY, Sim BKL, Cheng X, Zhang Z, Mitra K, Nakamura T, Takahashi H, Loomba R, Zheng MH, Muthiah M, Huang DQ.   +19 more
europepmc   +1 more source

Antimicrobial Susceptibility Profile of Eggerthella lenta Isolated From Bloodstream and Abdominal Fluid Infections

iLABMED, EarlyView.
Antimicrobial susceptibility analysis of clinical Eggerthella lenta isolates. This study reviewed 36 E. lenta isolates from the bloodstream and abdominal fluids (2018–2024). Identification methods included VITEK 2 ANC, MALDI‐TOF, and 16S rRNA sequencing. Antimicrobial susceptibility testing using agar dilution followed CLSI and EUCAST guidelines.
Yuan Gao, Longfeng Qu, Shu Zhang, Cheng Cheng, Bin Tang   +4 more
wiley   +1 more source

Burden of illness for patients with primary biliary cholangitis: an observational study of clinical characteristics and healthcare resource utilization. [PDF]

J Comp Eff Res
Gish RG, MacEwan JP, Levine A, Lebovitch D, Bessonova L, Wheeler D, Nair R, Bonder A.   +7 more
europepmc   +1 more source

Clinical characteristics of patients with chronic hepatitis c infection at initial presentation to tertiary care in an Asian middle-income country [PDF]

, 2018
Azzeri, Amirah, Dahlui, Maznah, Kamarulzaman, Adeeba, McDonald, Scott A., Mohamed, Rosmawati, Shabaruddin, Fatiha Hana, Tan, Soek-Siam   +6 more
core  

Integrative cross‐tissue analysis unveils complement‐immunoglobulin augmentation and dysbiosis‐related fatty acid metabolic remodeling during mammalian aging

iMeta, EarlyView.
Our study provides a comprehensive multi‐omics profile of aging, integrating proteomic, metabolomic, and metagenomic analyses across diverse tissues and plasma. We identified the synergistic amplification of the circulating complement system and tissue‐wide immunoglobulin accumulation as key molecular drivers of inflammaging.
Feng Zhang, Rong Li, Yasong Liu, Jinliang Liang, Yihang Gong, Cuicui Xiao, Jianye Cai, Tingting Wang, Qiang You, Jiebin Zhang, Haitian Chen, Jiaqi Xiao, Yingcai Zhang, Yang Yang, Hua Li, Jia Yao, Qi Zhang, Jun Zheng   +17 more
wiley   +1 more source

Clinical efficacy of transjugular intrahepatic portosystemic shunt in treating esophageal variceal bleeding in patients with liver cirrhosis. [PDF]

Pak J Med Sci
Zhao Q, Zi Q, Dong G, Lu Y, Zhang Y.
europepmc   +1 more source

Racing toward the future of chronic hepatitis B management: Achieving functional cure and enhancing hepatocellular carcinoma surveillance through precision medicine

Interdisciplinary Medicine, EarlyView.
Novel biomarker emergence plays a critical role in improving CHB management. Advances in sensitive detection methods, AI, and large‐scale data platforms have independently contributed to biomarkers while driving the development of multi‐omics approaches.
Yaru Shi, Rong Fan
wiley   +1 more source