Aspartate Aminotransferase to Platelet Ratio Index (APRI), Göteborg University Cirrhosis Index (GUCI), and Fibrosis 4 Score (FIB-4) proved to be the optimal biomarkers for the assessment of liver fibrosis in patients chronically infected with hepatitis C virus in Brazil. [PDF]
Dantas BP +5 more
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Oculometric Assessment of Sensorimotor Impairment Associated with Liver Disease Is as Sensitive as Standard of Care Cognitive Tests. [PDF]
Liston D +7 more
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Screening of advanced fibrosis and metabolic dysfunction-associated steatotic liver disease using transient elastography in vulnerable population. [PDF]
Nastasa R +11 more
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Cirrhosis is widely prevalent worldwide and can be a consequence of different causes, such as obesity, non-alcoholic fatty liver disease, high alcohol consumption, hepatitis B or C infection, autoimmune diseases, cholestatic diseases, and iron or copper overload.
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Cirrhosis-associated immune dysfunction
Nature Reviews Gastroenterology and Hepatology, 2021Agustín Albillos +2 more
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Cirrhosis is a chronic condition resulting from inflammation and fibrosis of the liver. Patients with cirrhosis may have a myriad of physical examination findings that reflect the severity of the underlying liver disease. Although many signs and symptoms related to cirrhosis are nonspecific, such as abdominal pain, nausea, and malaise, some findings ...
Rachel, Wilson, Donna M, Williams
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Utilizing the gut microbiome in decompensated cirrhosis and acute-on-chronic liver failure
Nature Reviews Gastroenterology and Hepatology, 2020Jonel Trebicka +2 more
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Conversion of Micronodular Cirrhosis into Macronodular Cirrhosis [PDF]
The conversion from micro- to macronodular cirrhosis is claimed to be a general phenomenon. In this study, the conversion was quantitated by means of liver needle follow-up biopsies and autopsy in 156 patients followed in a controlled clinical trial of prednisone treatment in cirrhosis.
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Infection is a well-described complication of cirrhosis and is a major cause of death in this population. This article examines the types of infections related with cirrhosis, such as bacteremia, urinary tract infections, meningitis, and others.
Diane H. Johnson, Burke A. Cunha
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