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AGA Clinical Practice Update: Coagulation in Cirrhosis.
Gastroenterology, 2019DESCRIPTION This expert review was commissioned and approved by the AGA Institute Clinical Practice Updates Committee and the AGA Governing Board to provide timely guidance on a topic of high clinical importance to the AGA membership.
J. O’Leary +3 more
semanticscholar +1 more source
Disease-a-Month, 2008
common causes of cirrhosis in the United States are alcoholic liver disease and chronic viral hepatitis. Other causes of cirrhosis are shown in Table 1. The pathogenesis of fibrosis is complex and largely unknown, but central to the process is inflammation and subsequent repair. Local and distal inflammatory cells are recruited, and tissue fibroblasts (
Sammy Saab, Mamie H. Dong
openaire +3 more sources
common causes of cirrhosis in the United States are alcoholic liver disease and chronic viral hepatitis. Other causes of cirrhosis are shown in Table 1. The pathogenesis of fibrosis is complex and largely unknown, but central to the process is inflammation and subsequent repair. Local and distal inflammatory cells are recruited, and tissue fibroblasts (
Sammy Saab, Mamie H. Dong
openaire +3 more sources
The American Journal of Nursing, 1965
T.aennec named the firm, diffusely fibrotic liver with its orange-colored projecting nodules "cirrhosis," after the Greek word kirrhos, meaning orange. Other synonyms are portal cirrhosis, alcoholic (ethanolic) cirrhosis, fatty cirrhosis, atrophic cirrhosis, and "gin drinker's liver." Laennec's cirrhosis is a pathologic entity in which a varying degree
Mary T. Bielski, David W. Molander
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T.aennec named the firm, diffusely fibrotic liver with its orange-colored projecting nodules "cirrhosis," after the Greek word kirrhos, meaning orange. Other synonyms are portal cirrhosis, alcoholic (ethanolic) cirrhosis, fatty cirrhosis, atrophic cirrhosis, and "gin drinker's liver." Laennec's cirrhosis is a pathologic entity in which a varying degree
Mary T. Bielski, David W. Molander
openaire +3 more sources
Gastroenterology, 2019
Portal vein thrombosis unrelated to solid malignancy is common in patients with cirrhosis, but less frequently observed in patients without cirrhosis. Prompt diagnosis and management of acute symptomatic portal vein thrombosis are essential.
N. Intagliata, S. Caldwell, A. Tripodi
semanticscholar +1 more source
Portal vein thrombosis unrelated to solid malignancy is common in patients with cirrhosis, but less frequently observed in patients without cirrhosis. Prompt diagnosis and management of acute symptomatic portal vein thrombosis are essential.
N. Intagliata, S. Caldwell, A. Tripodi
semanticscholar +1 more source
Scintiphotography in Cirrhosis
Archives of Internal Medicine, 1968Gamma camera scintiphotography was employed to study 30 patients with alcoholic liver disease. Marked hepatomegaly was found in 40% and abnormally small livers in 27%. Splenic uptake was significant and demonstrable in 60% of the patients. Only 10% had palpable spleens.
Donald Golden +3 more
openaire +3 more sources
Ugeskrift for laeger, 2014
Cirrhosis of the liver is a frequent and dangerous disease that causes numerous clinical contacts due to its complications. Competent and fast clinical decisions are often necessary in the acute setting and a broad clinical approach for the long-term problems due to the co-morbidity.
Bendtsen, Flemming +3 more
openaire +2 more sources
Cirrhosis of the liver is a frequent and dangerous disease that causes numerous clinical contacts due to its complications. Competent and fast clinical decisions are often necessary in the acute setting and a broad clinical approach for the long-term problems due to the co-morbidity.
Bendtsen, Flemming +3 more
openaire +2 more sources
Gastroenterology, 2018
BACKGROUND & AIMS Lysyl oxidase-like 2 contributes to fibrogenesis by catalyzing cross-linkage of collagen. We evaluated the safety and efficacy of simtuzumab, a monoclonal antibody against lysyl oxidase-like 2, in two phase 2b trials of patients with ...
Stephen A. Harrison +20 more
semanticscholar +1 more source
BACKGROUND & AIMS Lysyl oxidase-like 2 contributes to fibrogenesis by catalyzing cross-linkage of collagen. We evaluated the safety and efficacy of simtuzumab, a monoclonal antibody against lysyl oxidase-like 2, in two phase 2b trials of patients with ...
Stephen A. Harrison +20 more
semanticscholar +1 more source
Current Opinion in Gastroenterology, 2012
Chronic liver disease (CLD) causes significant morbidity and mortality, mainly due to complications [hepatic encephalopathy, ascites, hepatorenal syndrome (HRS), and esophageal variceal hemorrhage (EVH)]. Studies of the complications, management and outcomes in patients with CLD over the past 18 months are reviewed.Percutaneous liver biopsy can be ...
Don C. Rockey, Robert S. Rahimi
openaire +3 more sources
Chronic liver disease (CLD) causes significant morbidity and mortality, mainly due to complications [hepatic encephalopathy, ascites, hepatorenal syndrome (HRS), and esophageal variceal hemorrhage (EVH)]. Studies of the complications, management and outcomes in patients with CLD over the past 18 months are reviewed.Percutaneous liver biopsy can be ...
Don C. Rockey, Robert S. Rahimi
openaire +3 more sources