Results 31 to 40 of about 329,542 (317)

Characteristics of bacterial infections and prevalence of multidrug-resistant bacteria in hospitalized patients with liver cirrhosis in Germany

Annals of Hepatology, 2022
Introduction and Objectives: Bacterial infections are associated with a dismal prognosis in patients with liver cirrhosis. Data on their prevalence and the associated pathogen spectra in Germany are scarce.
Wolfgang Maximilian Kremer, Simon Johannes Gairing, Leonard Kaps, Esmeralda Ismail, Vasiliki Kalampoka, Max Hilscher, Maurice Michel, Ekkehard Siegel, Jörn M. Schattenberg, Peter R. Galle, Martin F. Sprinzl, Marcus-Alexander Wörns, Michael Nagel, Christian Labenz   +13 more
doaj   +1 more source

Drug-related problems and dosage adjustment in patients with liver disease [PDF]

, 2012
The liver is essential for the metabolism of medicinal substances. Liver disease, especially liver cirrhosis, may lead to various pharmacokinetic and pharmacodynamic changes, predisposing patients with liver cirrhosis to adverse drug events (ADEs).
Franz, Carmen Carina
core   +1 more source

Inhibitory effects of HNF4α on migration/maltransformation of hepatic progenitors: HNF4α-overexpressing hepatic progenitors for liver repopulation

Stem Cell Research & Therapy, 2017
Background Although they are expandable in vitro, hepatic progenitors are immature cells and share many immunomarkers with hepatocellular carcinoma, raising potential concerns regarding maltransformation after transplantation. This study investigated the
Ping Wang, Min Cong, Tianhui Liu, Hufeng Xu, Lin Wang, Guangyong Sun, Aiting Yang, Dong Zhang, Jian Huang, Yameng Sun, Wenshan Zhao, Hong Ma, Jidong Jia, Hong You   +13 more
doaj   +1 more source

Preoperative TIPS prevents the development of postoperative acute-on-chronic liver failure in patients with high CLIF-C AD score

JHEP Reports, 2022
Background & Aims: Acute-on-chronic liver failure (ACLF) is a syndrome associated with organ failure and high short-term mortality. Recently, the role of surgery as a precipitating event for ACLF has been characterised.
Johannes Chang, Pauline Höfer, Nina Böhling, Philipp Lingohr, Steffen Manekeller, Jörg C. Kalff, Jonas Dohmen, Dominik J. Kaczmarek, Christian Jansen, Carsten Meyer, Christian P. Strassburg, Jonel Trebicka, Michael Praktiknjo   +12 more
doaj   +1 more source

Medical treatment of ascites in cirrhosis [PDF]

, 1993
Medical treatment of cirrhotic ascites is essentially supportive, dictated by the patient's discomfort, impaired cardiovascular or respiratory function and potential for infection. Treatment of ‘simple’ ascites (moderate fluid accumulation, serum albumin
Gerbes, Alexander L.
core   +1 more source

Autologous Bone Marrow Infusion Activates the Progenitor Cell Compartment in Patients with Advanced Liver Cirrhosis

Cell Transplantation, 2010
Several clinical trials of bone marrow cell infusion in patients with liver cirrhosis (LC) have shown clinical improvement, despite conflicting results from animal models.
Ja Kyung Kim, Young Nyun Park, Jin Seok Kim, Mi-Suk Park, Yong Han Paik, Jae-Yeon Seok, Yong Eun Chung, Hyun Ok Kim, Kyung Sik Kim, Sang Hoon Ahn, Do Young Kim, Myeong-Jin Kim, Kwan Sik Lee, Chae Yoon Chon, Soo Jeong Kim, Shuji Terai, Isao Sakaida, Kwang-Hyub Han   +17 more
doaj   +1 more source

Albumin-bilirubin score for predicting the in-hospital mortality of acute upper gastrointestinal bleeding in liver cirrhosis: A retrospective study

The Turkish Journal of Gastroenterology, 2016
Background/Aims: The albumin-bilirubin (ALBI) score is a new model for assessing the severity of liver dysfunction. In the present study, we aimed to retrospectively compare the performance of ALBI with Child-Pugh and the model for end-stage liver ...
Deli Zou, Xingshun Qi, Cuihong Zhu, Zheng Ning, Feifei Hou, Jiancheng Zhao, Ying Peng, Jing Li, Han Deng, Xiaozhong Guo   +9 more
doaj   +1 more source

Correlation of Serum Cardiac Markers with Acute Decompensating Events in Liver Cirrhosis

Gastroenterology Research and Practice, 2020
Background and Aim. Liver cirrhosis is often accompanied by insidious cardiac dysfunction. This retrospective cross-sectional study is aimed at exploring the correlation between serum cardiac markers and decompensating events in liver cirrhosis. Methods.
Miaomiao Li, Zeqi Guo, Dan Zhang, Xiangbo Xu, Fernando Gomes Romeiro, Andrea Mancuso, Jingqiao Zhang, Ruirui Feng, Xinmiao Zhou, Cen Hong, Xingshun Qi   +10 more
doaj   +1 more source

Regression of liver fibrosis: evidence and challenges

Chinese Medical Journal, 2020
. It has been reported that liver fibrosis could be reversed after eliminating liver injuries. This article systematically summarizes the evidence of fibrosis regression based on histology, liver stiffness, and serum biomarkers, and discusses several ...
Ya-Meng Sun, Shu-Yan Chen, Hong You, Qiang Shi   +3 more
doaj   +1 more source

IDH Mutation Subgroup Status Associates with Intratumor Heterogeneity and the Tumor Microenvironment in Intrahepatic Cholangiocarcinoma

Advanced Science, 2021
Intrahepatic cholangiocarcinoma (ICC) is highly heterogeneous. Here, the authors perform exome sequencing and bulk RNA sequencing on 73 tumor regions from 14 ICC patients to portray the multi‐faceted intratumor heterogeneity (ITH) landscape of ICC.
Xiao Xiang, Ziyang Liu, Chong Zhang, Zhao Li, Jie Gao, Changkun Zhang, Qi Cao, Jinghui Cheng, Hengkang Liu, Dingbao Chen, Qian Cheng, Ning Zhang, Ruidong Xue, Fan Bai, Jiye Zhu   +14 more
doaj   +1 more source