Results 21 to 30 of about 5,595 (162)

Hepatitis C Virus Infection: Looking for Interferon Free Regimens

The Scientific World Journal, Volume 2013, Issue 1, 2013., 2013
Recent developments of new drugs′ combinations are changing the treatment paradigm in hepatitis C virus infection. Due to the side effect profile of pegylated interferons, interferon‐sparing regimens have become the main target in chronic hepatitis C treatment research.
J. González-Moreno, A. Payeras-Cifre, Han Chieh Lin, Sheng-Nan Lu   +3 more
wiley   +1 more source

Introducing Polyautoimmunity: Secondary Autoimmune Diseases No Longer Exist

Autoimmune Diseases, Volume 2012, Issue 1, 2012., 2012
Similar pathophysiological mechanisms within autoimmune diseases have stimulated searches for common genetic roots. Polyautoimmunity is defined as the presence of more than one autoimmune disease in a single patient. When three or more autoimmune diseases coexist, this condition is called multiple autoimmune syndrome (MAS).
Adriana Rojas-Villarraga, Jenny Amaya-Amaya, Alberto Rodriguez-Rodriguez, Rubén D. Mantilla, Juan-Manuel Anaya, Mario García-Carrasco   +5 more
wiley   +1 more source

Toll‐Like Receptors in Secondary Obstructive Cholangiopathy

Gastroenterology Research and Practice, Volume 2011, Issue 1, 2011., 2011
Secondary obstructive cholangiopathy is characterized by intra‐ or extrahepatic bile tract obstruction. Liver inflammation and structural alterations develop due to progressive bile stagnation. Most frequent etiologies are biliary atresia in children, and hepatolithiasis, postcholecystectomy bile duct injury, and biliary primary cirrhosis in adults ...
A. G. Miranda-Díaz, H. Alonso-Martínez, J. Hernández-Ojeda, O. Arias-Carvajal, A. D. Rodríguez-Carrizalez, L. M. Román-Pintos, A. Castells   +6 more
wiley   +1 more source

Serum Natrium Determines Outcome of Treatment of Advanced GIST with Imatinib: A Retrospective Study of 80 Patients from a Single Institution

International Scholarly Research Notices, Volume 2011, Issue 1, 2011., 2011
Treatment with tyrosine kinase inhibitors (TKIs) has drastically improved overall survival (OS) of patients with advanced GIST. The aim of this study is to evaluate the results of treatment with different TKIs on advanced GIST and identify prognostic factors for OS.
Ninna Aggerholm-Pedersen, Peter Rasmussen, Helle Dybdahl, Philip Rossen, Ole Steen Nielsen, Akmal Safwat, C. N. Qian, L. Saragoni   +7 more
wiley   +1 more source

Caffeine′s Vascular Mechanisms of Action

International Journal of Vascular Medicine, Volume 2010, Issue 1, 2010., 2010
Caffeine is the most widely consumed stimulating substance in the world. It is found in coffee, tea, soft drinks, chocolate, and many medications. Caffeine is a xanthine with various effects and mechanisms of action in vascular tissue. In endothelial cells, it increases intracellular calcium stimulating the production of nitric oxide through the ...
Darío Echeverri, Félix R. Montes, Mariana Cabrera, Angélica Galán, Angélica Prieto, Raphael Guzman   +5 more
wiley   +1 more source

Effects of the Japanese Herbal Medicine “Sho‐saiko‐to” (TJ‐9) on Interleukin‐12 Production in Patients with HCV‐Positive Liver Cirrhosis

Journal of Immunology Research, Volume 7, Issue 1, Page 17-22, 1999., 1998
Interleukin‐12 (IL‐12) is an important cytokine for maintainence of normal systemic defense and bioregulation. The Japanese herbal medicine Sho‐saiko‐to (TJ‐9) has been administered to 1.5 million Japanese patients with chronic liver diseases. TJ‐9 is known to significantly suppress cancer development in the liver and has macrobiotic effects.
Masayoshi Yamashiki, Akira Nishimura, Xian-Xi Huang, Tsutomu Nobori, Seigo Sakaguchi, Hiroyuki Suzuki   +5 more
wiley   +1 more source

Liver cirrosis and complication risk management

Terapevticheskii arkhiv, 2021
Liver cirrhosis (LC) takes the main place in the structure of the pathology of the digestive system in terms of the frequency of mortality, as well as in the development of fatal and poorly controlled complications, which requires the search for effective methods for preventing the progression of the disease and the development of complications.
Igor G. Bakulin, Inna A. Oganezova, Maria I. Skalinskaya, Ekaterina V. Skazyvaeva   +3 more
openaire   +4 more sources

Inmunología de la cirrosis hepática y sus tratamientos. [PDF]

, 2021
La cirrosis hepática es una condición clínica caracterizada por la incapacidad del hígado de funcionar de manera correcta debido a un daño hepático ocasionado durante un largo periodo de tiempo.
Martínez Redondo, José Antonio
core   +1 more source

An Exploratory Study on the Pathogenic Role of Faecal Extracellular Vesicles in Metabolic Dysfunction‐Associated Steatotic Liver Disease Progression and in Drug‐Induced Liver Injury

Journal of Extracellular Vesicles, Volume 15, Issue 3, March 2026.
Fecal extracellular vesicles (fEVs) from DILI patients have a distinct bacterial profile. This study provides evidence that bacterial EVs enter the bloodstream. DILI and MASLD F≥3 fEVs increase the pro‐inflammatory response and hepatocyte steatosis. FEVs from DILI patients enhance the hepatotoxic potential of diclofenac.
Antonio J. Ruiz‐Malagón, Marina Herraiz‐Vilela, Jose Pinazo‐Bandera, Juan Pedro Toro‐Ortiz, Carlos López‐Gómez, Ailec Ho‐Plagaro, Lourdes Garrido‐Sánchez, Mercedes Robles‐Díaz, Bernard Taminiau, Georges Daube, Judith Sanabria‐Cabrera, Gonzalo Matilla‐Cabello, Maria Isabel Lucena, Raúl J. Andrade, Eduardo García‐Fuentes, Miren García‐Cortes, Cristina Rodriguez‐Diaz   +16 more
wiley   +1 more source

The Economics of Liver Fibrosis Diagnosis: Systematic Review of Non‐Invasive Test Cost‐Effectiveness

Liver International Communications, Volume 6, Issue 4, December 2025.
ABSTRACT Hepatic diseases progress silently, leading to fibrosis, cirrhosis, and hepatocellular carcinoma. Although liver biopsy remains the gold standard for fibrosis assessment, it is limited by invasiveness and sampling variability. Non‐invasive liver tests (NILTs) can mitigate biopsy‐related risks.
Marilia Mastrocolla de Almeida Cardoso, Fernando Gomes Romeiro, Wendel Mombaque dos Santos, Juliana Machado‐Rugolo, Juliana Tereza Coneglian de Almeida, Lehana Thabane, Kednapa Thavorn, Jean‐Eric Tarride   +7 more
wiley   +1 more source