Results 21 to 30 of about 1,271 (178)

Serum Natrium Determines Outcome of Treatment of Advanced GIST with Imatinib: A Retrospective Study of 80 Patients from a Single Institution

International Scholarly Research Notices, Volume 2011, Issue 1, 2011., 2011
Treatment with tyrosine kinase inhibitors (TKIs) has drastically improved overall survival (OS) of patients with advanced GIST. The aim of this study is to evaluate the results of treatment with different TKIs on advanced GIST and identify prognostic factors for OS.
Ninna Aggerholm-Pedersen, Peter Rasmussen, Helle Dybdahl, Philip Rossen, Ole Steen Nielsen, Akmal Safwat, C. N. Qian, L. Saragoni   +7 more
wiley   +1 more source

Caffeine′s Vascular Mechanisms of Action

International Journal of Vascular Medicine, Volume 2010, Issue 1, 2010., 2010
Caffeine is the most widely consumed stimulating substance in the world. It is found in coffee, tea, soft drinks, chocolate, and many medications. Caffeine is a xanthine with various effects and mechanisms of action in vascular tissue. In endothelial cells, it increases intracellular calcium stimulating the production of nitric oxide through the ...
Darío Echeverri, Félix R. Montes, Mariana Cabrera, Angélica Galán, Angélica Prieto, Raphael Guzman   +5 more
wiley   +1 more source

Liver cirrosis and complication risk management

Terapevticheskii arkhiv, 2021
Liver cirrhosis (LC) takes the main place in the structure of the pathology of the digestive system in terms of the frequency of mortality, as well as in the development of fatal and poorly controlled complications, which requires the search for effective methods for preventing the progression of the disease and the development of complications.
Igor G. Bakulin, Inna A. Oganezova, Maria I. Skalinskaya, Ekaterina V. Skazyvaeva   +3 more
openaire   +4 more sources

Effects of the Japanese Herbal Medicine “Sho‐saiko‐to” (TJ‐9) on Interleukin‐12 Production in Patients with HCV‐Positive Liver Cirrhosis

Journal of Immunology Research, Volume 7, Issue 1, Page 17-22, 1999., 1998
Interleukin‐12 (IL‐12) is an important cytokine for maintainence of normal systemic defense and bioregulation. The Japanese herbal medicine Sho‐saiko‐to (TJ‐9) has been administered to 1.5 million Japanese patients with chronic liver diseases. TJ‐9 is known to significantly suppress cancer development in the liver and has macrobiotic effects.
Masayoshi Yamashiki, Akira Nishimura, Xian-Xi Huang, Tsutomu Nobori, Seigo Sakaguchi, Hiroyuki Suzuki   +5 more
wiley   +1 more source

An Exploratory Study on the Pathogenic Role of Faecal Extracellular Vesicles in Metabolic Dysfunction‐Associated Steatotic Liver Disease Progression and in Drug‐Induced Liver Injury

Journal of Extracellular Vesicles, Volume 15, Issue 3, March 2026.
Fecal extracellular vesicles (fEVs) from DILI patients have a distinct bacterial profile. This study provides evidence that bacterial EVs enter the bloodstream. DILI and MASLD F≥3 fEVs increase the pro‐inflammatory response and hepatocyte steatosis. FEVs from DILI patients enhance the hepatotoxic potential of diclofenac.
Antonio J. Ruiz‐Malagón, Marina Herraiz‐Vilela, Jose Pinazo‐Bandera, Juan Pedro Toro‐Ortiz, Carlos López‐Gómez, Ailec Ho‐Plagaro, Lourdes Garrido‐Sánchez, Mercedes Robles‐Díaz, Bernard Taminiau, Georges Daube, Judith Sanabria‐Cabrera, Gonzalo Matilla‐Cabello, Maria Isabel Lucena, Raúl J. Andrade, Eduardo García‐Fuentes, Miren García‐Cortes, Cristina Rodriguez‐Diaz   +16 more
wiley   +1 more source

The Economics of Liver Fibrosis Diagnosis: Systematic Review of Non‐Invasive Test Cost‐Effectiveness

Liver International Communications, Volume 6, Issue 4, December 2025.
ABSTRACT Hepatic diseases progress silently, leading to fibrosis, cirrhosis, and hepatocellular carcinoma. Although liver biopsy remains the gold standard for fibrosis assessment, it is limited by invasiveness and sampling variability. Non‐invasive liver tests (NILTs) can mitigate biopsy‐related risks.
Marilia Mastrocolla de Almeida Cardoso, Fernando Gomes Romeiro, Wendel Mombaque dos Santos, Juliana Machado‐Rugolo, Juliana Tereza Coneglian de Almeida, Lehana Thabane, Kednapa Thavorn, Jean‐Eric Tarride   +7 more
wiley   +1 more source

Hepatitis y Cirrosis

Revista de Medicina de la Universidad de Navarra, 2016
Tras unas consideraciones generales acerca del concepto de cirrosis hepática, los autores estudian, entre 100 casos de cirrosis de Laennec, los antecedentes a los que atribuye un valor etiológico. En concreto, el padecimiento de una hepatitis se encontró en sólo 10 casos, por lo que los autores concluyen que, aún en el caso de que exista una ...
T.A Pinós, J. Illa Cantallops
openaire   +1 more source

Cirrosis de Laennec [PDF]

, 2021
Los médicos antiguos ya conocían el endurecimiento del hígado como final de una hepatopatía crónica, describiéndolo como un hígado duro, crugiante al corte, escirroso y con obstrucción hepática. Entre otros, Besal (1515-1564) y Morgagni (1652-1771) ya describieron retracciones hepáticas observadas en sus autopsias.
openaire   +2 more sources

Cirrosis, la nueva problemática que afecta a niños y adolescentes.

Ateneo, 2023
RESUMEN Antecedentes: La cirrosis es la etapa final de una alteración crónica presentada a nivel del hígado, cuya supervivencia es menor a los 3 años una vez que esta se encuentre descompensada, es la consecuencia de múltiples factores, entre los ...
Diego Andrade, Joseph Coronel, Anabel Lopez, Nayerly Maldonado, Carlos Martinez   +4 more
doaj  

Caracterización epidemiológica y clínica de la cirrosis hepatica en un centro regional del caribe colombiano: clínica general del norte. Enero 2012 a marzo 2017

Biociencias, 2018
La cirrosis hepática es una de las enfermedades con mayor prevalencia y mortalidad en la población mundial; sus etiologías más importantes son de tipo alcohólica, el virus de la hepatitis B, el virus de la hepatitis C y la esteatosis hepática no ...
Edgardo Jose Escorcia Charri
doaj   +1 more source