Results 31 to 40 of about 734,495 (266)

rac-cis-Cyclohexane-1,2-dicarboxylic acid–isoquinoline (1/1)

open access: yesActa Crystallographica Section E, 2011
In the crystal structure of the title molecular adduct, C9H7N·C8H12O4, the two species are linked through a carboxylic acid–isoquinoline O—H...N hydrogen bond.
Graham Smith, Urs D. Wermuth
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

rac-4-Carbamoylpiperidinium cis-2-carboxycyclohexane-1-carboxylate

open access: yesActa Crystallographica Section E, 2012
In the title racemic salt, C6H13N2O+·C8H11O4−, formed from the reaction of cis-cyclohexane-1,2-dicarboxylic anhydride with isonipecotamide, the cations are linked into duplex chain substructures through both centrosymmetric cyclic head-
Graham Smith, Urs D. Wermuth
doaj   +1 more source

In Situ Photodeposition of Cobalt Phosphate (CoHxPOy) on CdIn2S4 Photocatalyst for Accelerated Hole Extraction and Improved Hydrogen Evolution

open access: yesNanomaterials, 2023
The ternary metal sulfide CdIn2S4 (CIS) has great application potential in solar-to-hydrogen conversion due to its suitable band gap, good stability and low cost.
Jiachen Xu   +10 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

rac-2-Aminopyridinium cis-2-carboxycyclohexane-1-carboxylate

open access: yesActa Crystallographica Section E, 2011
In the structure of the title compound, C5H7N2+·C8H11O4−, the cis anions associate through head-to-tail carboxylic acid–carboxyl O—H...O hydrogen bonds [graph set C(7)], forming chains which extend along c and are ...
Graham Smith, Urs D. Wermuth
doaj   +1 more source

Toward a Lattice Boltzmann Method for Solids—Application to Static Equilibrium of Isotropic Materials

open access: yesApplied Sciences, 2022
This work presents a novel method for simulating the behavior of solid objects with the Lattice Boltzmann Method (LBM). To introduce and validate our proposed framework, comparative studies are performed for computing the static equilibrium of isotropic ...
Tristan Maquart   +3 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

rac-cis,cis-Dicarbonyldichlorido{1-[2-(diphenylphosphanyl)benzyl]-3-mesitylimidazol-2-ylidene}ruthenium(II) dichloromethane monosolvate

open access: yesActa Crystallographica Section E, 2012
The RuII atom in the title compound, [RuCl2(C31H29N2P)(CO)2]·CH2Cl2, exhibits a distorted octahedral coordination environment. The bond angles of the cis substituents at the RuII atom range from 82.72 (9) to 97.20 (3)& ...
Gregory J. Domski   +2 more
doaj   +1 more source

Integrated analysis of lncRNA, miRNA and mRNA profiles reveals potential lncRNA functions during early HIV infection

open access: yesJournal of Translational Medicine, 2021
Background Long noncoding RNAs (lncRNAs) can regulate gene expression in a cis-regulatory fashion or as “microRNA sponges”. However, the expression and functions of lncRNAs during early human immunodeficiency virus (HIV) infection (EHI) remain unclear ...
Lianwei Ma   +9 more
doaj   +1 more source

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