Cancer Science, Volume 117, Issue 4, Page 996-1009, April 2026.Overexpression of ABC transporters, especially ABCG2 and ABCB1, mediates acquired resistance to T‐DXd in HER2‐positive cancers. Inhibition of these transporters restored T‐DXd efficacy, highlighting efflux‐mediated resistance as a potential therapeutic target. ABSTRACT Antibody–drug conjugates (ADCs) are emerging as a promising class of targeted cancer
Yuya Murase +23 more
wiley +1 more source
A short historical overview on the use of lead [PDF]
, 2018 This historical introduction to the use of lead in art and technology was originally written to give context to lead conservation studies by the authors.
Adriaens, Mieke +2 more
core +1 more source
Disasters, Volume 50, Issue 2, April 2026.Abstract Our understanding of the effects of multi‐hazard contexts on risk perception and behaviour is limited. In a novel approach, we utilise an experimental survey where groups of participants are asked to consider a different combination of the same two hazards: an earthquake and a tsunami.
Lauren J. Vinnell +2 more
wiley +1 more source
Genetic Diversity Impacts Climate‐Induced Species Range Shifts
Ecology Letters, Volume 29, Issue 4, April 2026.Genetic diversity may buffer species against climate‐driven range contractions and facilitate expansions, but its role at a global scale remains unclear. Using 4673 range shift estimates for 1888 species, we show that higher genetic diversity reduces trailing edge contractions under rapid warming and accelerates leading edge expansions under moderate ...
Brunno F. Oliveira +17 more
wiley +1 more source
FinTech Lending and Cashless Payments
The Journal of Finance, Volume 81, Issue 2, Page 1053-1101, April 2026.ABSTRACT Borrowers' use of cashless payments improves their access to capital from FinTech lenders and predicts a lower probability of default. These relationships are stronger for cashless technologies providing more precise information, and for outflows. Cashless payment usage complements other signals of borrower quality.
PULAK GHOSH, BORIS VALLEE, YAO ZENG
wiley +1 more source
The Journal of Physiology, Volume 604, Issue 7, Page 3032-3052, 1 April 2026.Abstract figure legend In cortical layer (L)5 pyramidal neurons we found that mitochondria in the axon initial segment (AIS) are distributed non‐uniformly and display robust calcium (Ca2+) uptake during action potential (AP) firing. Because the AIS is the site for the initiation of APs, which are shaped by cytosolic Ca2+ levels, we hypothesized that ...
Koen Kole, Maarten H.P. Kole
wiley +1 more source
Extended endoscopic endonasal transplanum-transtuberculum surgery for optic pathway-hypothalamic glioma presenting with tonsillar herniation and syringomyelia: illustrative case. [PDF]
J Neurosurg Case LessonsNakano Y, Suzuki K, Inoue M, Yamamoto J.
europepmc +1 more source
Radiologic Characteristics and Clinical Correlates of Quadrigeminal Cistern Arachnoid Cysts: A Retrospective Study. [PDF]
CureusAzizi F, Karatay E, Eren A, Karacay E.
europepmc +1 more source
Hyperbaric Oxygen Therapy in Postoperative Intracranial Pneumocephalus After Lumbar Decompression: A Case Study. [PDF]
Int Med Case Rep JChen Z +6 more
europepmc +1 more source
Successfully treated delayed upward trans-tentorial herniation (UTTH) following ventriculoperitoneal shunt placement for an acute obstructive hydrocephalus secondary to midline posterior fossa mass in a low-resource setting: case report. [PDF]
Int J Surg Case RepYesuf EF, Zewdie AZ, Shiferaw MY.
europepmc +1 more source