Results 131 to 140 of about 15,137 (245)

Vacuolization as a Novel Approach to Cancer Therapy

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 6, June 2026.
This review discusses the novel strategy of inducing vacuole formation in cancer cells using small molecules, that induce nonapoptotic cell death mechanisms, such as paraptosis, oncosis, autophagy, and methuosis, and its potential in overcoming resistance to apoptosis‐based cancer therapies.
Mariah Pasternak, Noor Hussein, Veronica Piedra, Saloni Malla, Chandrabose Karthikeyan, Haneen Amawi, Harish Rajak, Charles R. Ashby Jr., R. Jayachandra Babu, Amit K. Tiwari   +9 more
wiley   +1 more source

The effect of staphylococcal infection on cathelicidin and β-defensin mRNA levels in epithelial cells lining the mammary gland cistern. [PDF]

Front Immunol
Bagnicka E, Szprynca A, Kościuczuk E, Jarczak J, Rzewuska M, Sakowski T, Zalewska M.   +6 more
europepmc   +1 more source

Extracellular Vesicle‐Associated IL4 Displays Enhanced Anti‐Inflammatory Properties in Microglial Cells

Journal of Extracellular Biology, Volume 5, Issue 6, June 2026.
ABSTRACT Neuroinflammation and neurodegeneration are strictly related phenomena, characterized by dysregulation of microglia, central nervous system (CNS) resident immune cells. Interleukin‐4 (IL4) has shown beneficial abilities to re‐establish microglial homeostasis in experimental models of CNS traumatic injury, stroke and multiple sclerosis, but its
Giulia Marostica, Chiara Frigè, Annamaria Finardi, Alessandra Mandelli, Susanna Manenti, Stella Siciliani, Paola Podini, Ivan De Curtis, Luca Muzio, Elena Rossi, Paola de Candia, Roberto Furlan   +11 more
wiley   +1 more source

Ecchordosis physaliphora presenting with cerebrospinal fluid leak and meningitis: illustrative case. [PDF]

J Neurosurg Case Lessons
Balasubramanian K, Zuccato JA, El Rassi E, Dunn IF.   +3 more
europepmc   +1 more source

EV‐SPEC: Decoding the Spatial Proteomic Signature of the Extracellular Vesicle Corona

Journal of Extracellular Biology, Volume 5, Issue 6, June 2026.
This study introduces ‘EV‑SPEC’, a spatial proteomics method using TurboID fused to the transmembrane protein CD63 to map the protein corona of extracellular vesicles (EVs) without physical isolation. We show that EV‐SPEC identifies the protein‐protein interaction footprint of serum proteins, similar to those typically found on synthetic nanoparticles,
Camille Menaceur Vandenbroucke, Carsten Scavenius, Yuya Hayashi   +2 more
wiley   +1 more source

Recurrent multiloculated cystic variant of Lhermitte-Duclos disease managed with cyst fenestration and Ommaya reservoir placement: illustrative case. [PDF]

J Neurosurg Case Lessons
Uchida D, Hiu T, Masui K, Yamaguchi R, Nakamura H, Takeuchi M, Shirahama M, Ogawa Y, Matsuo A, Matsunaga Y, Baba S, Ujifuku K, Yoshida K, Morofuji Y, Matsuo T.   +14 more
europepmc   +1 more source

Efficacy of a Quantitative Intra‐Operative Facial Nerve Continuous Monitoring System for Functional Preservation Following Intratemporal Facial Nerve Schwannoma Resection

Laryngoscope Investigative Otolaryngology, Volume 11, Issue 3, June 2026.
We investigated the role of a continuous, quantitative intraoperative monitoring system in surgeries for facial nerve schwannomas, a rare tumor associated with a high risk of facial nerve dysfunction. By continuously stimulating the facial nerve and recording electromyographic responses in real time, the system enabled surgeons to detect subtle or ...
Makoto Hosoya, Marie N. Shimanuki, Masafumi Ueno, Satoshi Suda, Takeshi Wakabayashi, Takanori Nishiyama, Hiroyuki Ozawa, Naoki Oishi   +7 more
wiley   +1 more source

Endovascular treatment for subarachnoid hemorrhage during pregnancy followed by minimum approaches for cerebral vasospasm. [PDF]

Surg Neurol Int
Maeoka R, Ohnishi H, Matsuda R, Nakagawa I.   +3 more
europepmc   +1 more source

Fascia‐Fat‐Fascia “Sandwich Graft” Decreases Postoperative Cerebrospinal Fluid Leak Rate for High‐Flow Skull Base Defects

International Forum of Allergy &Rhinology, Volume 16, Issue 6, Page 646-649, June 2026.
Vidit M. Talati, Kathy Zhang, Kimberly X. Wei, Margaret B. Mitchell, Nithin D. Adappa, Michael A. Kohanski, Jennifer E. Douglas, Christina Jackson, John Y. K. Lee, Phillip B. Storm, Jillian W. Lazor, James N. Palmer   +11 more
wiley   +1 more source

Pathways of Protein Secretion in Prokaryotes and Eukaryotes: Molecular Mechanisms, Biological Functions, and Therapeutic Opportunities

MedComm, Volume 7, Issue 6, June 2026.
This graphical abstract delineates noncanonical protein secretion systems across eukaryotes and prokaryotes. Eukaryotic UcPS covers four ER–Golgi bypass pathways, enabling rapid leaderless protein export via direct transmembrane translocation or vesicle‐mediated release.
Qiyuan Yang, Jingfei Shi, Linlin Xu, Guangrui Zhao, Yue Chen, Lin Cheng, Xiaokang Li, Zhigang Sun, Shuhong Huang   +8 more
wiley   +1 more source