Sustained delivery of a shingles subunit vaccine from an injectable polymer–nanoparticle hydrogel enhanced the potency, durability, and breadth of immune responses in aged mice while minimizing inflammatory cytokine production and reactogenicity. This strategy decouples immunogenicity from reactogenicity and offers a promising approach to improve ...
Ye Eun Song +5 more
wiley +1 more source
Research Progress of Sepsis and Nutrition: A Bibliometric and Visualized Analysis. [PDF]
Shang L +9 more
europepmc +1 more source
Dual Blockade of LILRB1 and LILRB2 Enhances Antiviral Immune Responses in SIV Infection
Dual LILRB1/B2 blockade with mac20G10 reshapes myeloid activation during acute SIV infection by targeting LILRB1 and LILRB2 on myeloid cells. This treatment enhances CD80 expression on selected myeloid subsets and increases plasma IFN‐λ, IL‐8, and IL‐1RA.
Florian Meurisse +20 more
wiley +1 more source
From fibrosis regression to recompensation: bibliometric and clinical evidence mapping of disease modification in cirrhosis. [PDF]
Zhang HW +10 more
europepmc +1 more source
Stereochemistry enables control of ion‐exchange membrane properties via local backbone flexibility without altering the polymer composition. Syn‐enriched membranes show higher water uptake and improved water‐electrolysis performance, whereas anti‐enriched membranes exhibit higher hydration efficiency and improved mechanical properties.
Si Chen +3 more
wiley +1 more source
Three decades of microcystin-LR removal in aquatic environments: physical, chemical and biological strategies for environmental detoxification. [PDF]
Zhong X, Zhang H, Xie P.
europepmc +1 more source
Closing the Empirical Loop: Autonomous AI Agents Conduct End‐to‐end Research With Human Participants
A multi‐agent AI system autonomously executes the complete scientific workflow, from hypothesis to manuscript, across three psychological studies involving 288 participants. The system designs experiments, collects real world data, develops analysis pipelines, and writes manuscripts with theoretical rigor comparable to experienced researchers.
Gabrielle Wehr +6 more
wiley +1 more source
Engineered bacterial therapeutics from synthetic biology to clinical translation: A multi-database scientometric analysis, 2000-2026. [PDF]
Zhou H +5 more
europepmc +1 more source
NSD2 coordinates the neurogenic‐to‐gliogenic transition in the developing neocortex through H3K36me2‐dependent activation of EGFR–ERK signaling. Loss of NSD2 disrupts astroglial and oligodendroglial development, whereas ERK activation rescues gliogenic defects in vitro and in vivo.
Hanxue Chen +7 more
wiley +1 more source
Orthopaedic publications receive fewer citations than general medicine articles: a scientometric analysis of temporal trends. [PDF]
Migliorini F +8 more
europepmc +1 more source

