Results 301 to 310 of about 5,319,795 (358)

SCRIPT: Predicting Single‐Cell Long‐Range Cis‐Regulation Based on Pretrained Graph Attention Networks

open access: yesAdvanced Science, EarlyView.
SCRIPT is a novel method inferring single‐cell cis‐regulatory relationships (CRRs) from transcriptomic and chromatin accessibility data. SCRIPT incorporates two key innovations: graph causal attention networks supported by empirical CRR evidence, and representation learning enhanced through pretraining on atlas‐scale single‐cell data.
Yu Zhang   +13 more
wiley   +1 more source

Tendinopathy: The Interplay between Mechanical Stress, Inflammation, and Vascularity

open access: yesAdvanced Science, EarlyView.
This review explores the complex and self‐reinforcing cycle of mechanical stress, inflammation, and altered vascularity in tendinopathy—a common, painful tendon disorder. It integrates current findings on cellular, molecular, and biomechanical mechanisms, highlighting how mechanical overload, inflammatory signals, and abnormal blood vessel behavior ...
Renate Gehwolf   +5 more
wiley   +1 more source

Molecular Damping Effect of Trace Additives Enhances Zinc Anode Stability Under High Depth of Discharge

open access: yesAdvanced Science, EarlyView.
Inspired by the energy dissipation from damping effects, this work employs trace amounts of weakly adsorbing additives to form an adapted interface on the Zn anode. Unlike the water‐deficient interfaces formed by strongly adsorbing additives, this adapted weakly adsorbing interface enables the regulation of electric field disturbances at higher depths ...
Yue Li   +8 more
wiley   +1 more source

Recent Developments in Nanoparticle‐Hydrogel Hybrid Materials for Controlled Release

open access: yesAdvanced Science, EarlyView.
This review highlights recent advances in nanoparticle–hydrogel hybrid materials for controlled drug delivery. It explores diverse nanocarrier–hydrogel combinations, drug loading strategies, release mechanisms, and stimuli‐responsive behaviors. Emphasis is placed on the molecular interactions driving hybrid material performance, offering insights into ...
Yiping Fan   +8 more
wiley   +1 more source

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