Results 41 to 50 of about 364,720 (248)

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

WATERFLOOD CONFORMANCE IMPROVEMENT – PRACTICAL CONSIDERATIONS & LESSONS LEARNED

open access: yesRevista Fuentes El Reventón Energético, 2018
Conformance improvement is commonly referred to as the action of improving the drive-fluid sweep efficiency during an oil-recovery flooding operation. This technical note highlights the authors lessons learned during the field application of one of the ...
Jay T Portwood, Jorge L Romero
doaj  

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

The Situation of Top Universities\\\' Websites in the Islamic World Countries: a Webometric Study

open access: yesIranian Journal of Information Processing & Management, 2011
With regards to important role of universities’ websites, this article aimed to study top universities of the Islamic countries using webometrics methods. Research data were extracted from AltaVista search engine and WEBOMETRICS website.
Marzieh Goltaji, Fereshteh Didegah
doaj  

Top web preservation programs’ solutions in facing technical challenges [PDF]

open access: yesتحقیقات کتابداری و اطلاع‌رسانی دانشگاهی, 2014
Objective: The present study aims to verify web preservation projects and programs in order to explore their preferred solutions in tackling the technical challenges.
Hajar Sotudeh, kianoosh Rashidi
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

The Situation of Top Research Centers' Websites in the Islamic World Countries: A Webometric Study

open access: yesInternational Journal of Information Science and Management, 2012
Research centers are among the most important institutes in a scientific society. Using the AltaVista search engine and webometric methods, this research tries to find the performance and impact of the top research centers of the Islamic World ...
M. Goltaji, M. Serati Shirazi
doaj  

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Eigenfactor: a New Measure for Assessing Scientific Publications

open access: yesIranian Journal of Information Processing & Management, 2011
Over the past decades, a number of measures for determining the impact of scientific journals were introduced and utilized. The number of citations and Impact Factor value are the indicators have been applied a lot in this area and are of a high ...
Seyyedeh Mojgan Binesh   +1 more
doaj  

A Genetic-based approach for Author Name Disambiguation Problem

open access: yesIranian Journal of Information Processing & Management, 2021
In the recent years, with the increasing volume of articles and the use of Internet and search engine services, the author name disambiguation problem has received a lot of attention.
Niloofar Mozafari
doaj  

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