Detection of Protein–Protein Interactions in Escherichia coli With Single Molecule Sensitivity
Advanced Science, EarlyView.This article describes a regulatory circuit in Escherichia coli able to detect protein–protein interactions with exquisite sensitivity. The interaction between two hybrid proteins fused to Bordetella pertussis adenylate cyclase and its activator calmodulin triggers a potent cyclic AMP signaling cascade.
Marilyne Davi, Daniel Ladant
wiley +1 more source
Practical Quantum Advantage for Boosting Citations
Realizing practical quantum advantage with meaningful economic impact is the holy grail of the quantum information field. Recent quantum technology advances have driven exponential growth in quantum information research, with resultant publications achieving significantly elevated impact.
openaire +2 more sources
Letter to the Editor about the article: <i>by C. Eskander, et al</i>, "Magnetocardiography for noninvasive surveillance of rejection and cardiac allograft vasculopathy in heart transplant recipients," <i>Am. Hear. J. Plus Cardiol. Res. Pract., vol. 62, p. 100704,…</i>. [PDF]
Am Heart J PlusBrisinda D, Fenici P, Fenici R.
europepmc +1 more source
Evaluating the Utilities of Foundation Models in Single‐Cell Data Analysis
Advanced Science, EarlyView.This study delivers the first systematic, task‐level evaluation of single‐cell foundation models across eight core analytical tasks. By benchmarking 10 leading models with the scEval framework, it reveals where foundation models truly add value, where task‐specific methods still dominate, and provides concrete, reproducible guidelines to steer the next
Tianyu Liu +4 more
wiley +1 more source
The controversies in the clinical management of β-blockers in acute heart failure induced by rapid atrial fibrillation: A narrative review. [PDF]
Am Heart J PlusZhu W, Xu J.
europepmc +1 more source
Advanced Science, EarlyView.Antibody–drug conjugates (ADCs) transform breast cancer therapy, yet resistance limits their durability. Emerging evidence reveals that ADC failure is not solely tumor‐intrinsic but shaped by dynamic tumor–microenvironment interactions that alter drug delivery, processing, and response.
Minji Seo, Jangsoon Lee, Naoto T. Ueno
wiley +1 more source
Beyond the First Impact Factor: Editorial Renewal and Direction in Thoracic Research and Practice. [PDF]
Thorac Res PractAkgün M, Ergan B.
europepmc +1 more source
Machine Learning for Green Solvents: Assessment, Selection and Substitution
Advanced Science, EarlyView.Environmental regulations have intensified demand for green solvents, but discovery is limited by Solvent Selection Guides (SSGs) that quantify solvent sustainability. Training a machine learning model on GlaxoSmithKline SSG, a database of sustainability metrics for 10,189 solvents, GreenSolventDB is developed. Integrated with Hansen solubility metrics,
Rohan Datta +4 more
wiley +1 more source
Hallucinated citations produced by generative artificial intelligence may constitute research misconduct when citations function as data in scholarly papers. [PDF]
Account ResResnik DB, Hosseini M.
europepmc +1 more source
Solid Harmonic Wavelet Bispectrum for Image Analysis
Advanced Science, EarlyView.The Solid Harmonic Wavelet Bispectrum (SHWB), a rotation‐ and translation‐invariant descriptor that captures higher‐order (phase) correlations in signals, is introduced. Combining wavelet scattering, bispectral analysis, and group theory, SHWB achieves interpretable, data‐efficient representations and demonstrates competitive performance across texture,
Alex Brown +3 more
wiley +1 more source