Results 121 to 130 of about 553,677 (293)
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
The need for energy-efficient buildings must be based on strong effective passive-design techniques, which coordinate indoor air quality and thermal comfort.
Antonio Sánchez Cordero +2 more
doaj +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
The Human Being in Exposure to Mystery: Phenomenological Foundations of a Mystical Anthropology
This article develops a phenomenological foundation of mystical anthropology through a dialogue between contemporary Spanish philosophy and the sixteenth-century Castilian mystical tradition.
Angélica Morales Arizmendi
doaj +1 more source
Implementasi CITES (Convention on International Trade in Endangered Species of Wild Fauna and Flora) dalam Menangani Perdagangan Kukang Ilegal di Indonesia [PDF]
Slow loris or Nycticebus sp is one of endemic primate animals in Indonesia. Since 2007, slow loris has been categorized into Appendix I CITES (Convention on International Trade in Endangered Species of Wild Fauna and Flora).
Wahyadyatmika , Permana Adi
core
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Canopy conductance is a crucial factor in modelling plant transpiration and is highly responsive to water stress. The objective of this study is to develop a straightforward method for estimating canopy conductance (gc) in grapevines. To predict gc, this
Ricardo Jorge Lopes Egipto +2 more
doaj +1 more source
Solar thermal heating and cooling. A bibliography with abstracts [PDF]
This bibliographic series cites and abstracts the literature and technical papers on the heating and cooling of buildings with solar thermal energy. Over 650 citations are arranged in the following categories: space heating and cooling systems; space ...
Arenson, M.
core +1 more source

