Results 121 to 130 of about 37,653 (264)

Herpes B virus and the neglected risk of zoonotic spillover. [PDF]

One Health
Kim Y, Lee JM, Hong JJ.
europepmc   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

On citing well [PDF]

Nature Chemical Biology, 2010
openaire   +2 more sources

Diseases and Mortality in Confiscated Birds and Reptiles Housed in a Wildlife Rescue Center Under the CITES Directive. [PDF]

Vet Sci
Martín A, Soto AR, Hidalgo-Martínez V, Rodríguez Luis A, Aranda Vázquez MDC, de Andrés Gamazo PJ, Jiménez Martínez MLÁ.   +6 more
europepmc   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Composition and Legal Aspects of Reptiles and Amphibians Displayed at an Exotic Pet Fair in Warsaw (Poland). [PDF]

Animals (Basel)
Zieliński D, Nawłatyna P, Wójcik Z.
europepmc   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

International trade regulations take a limited bite out of the shark fin trade. [PDF]

Sci Adv
Cardeñosa D, Babcock EA, Shea SK, Zhang H, Feldheim KA, Yang F, Gale SW, Fernando D, Tanna A, Warwick L, D Chapman D.   +10 more
europepmc   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Citing, being cited, not citing, and not being cited: Citations as intellectual footprints.

, 2017
Lavigne, Alyson Leah, Good, Thomas L.
openaire   +1 more source