Molecular Oncology, EarlyView.Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
Wildlife Trade and Genetic Basis of Disease Susceptibility: A Review. [PDF]
Int J ImmunogenetCoker OM, Fagbenro OS, Coker MM.
europepmc +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Following the <i>Bitis</i> pet trade: a practice-based exploration across Africa and Europe. [PDF]
Socioecol Pract ResHeim JB.
europepmc +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Insights from three decades of IUCN Red List assessments catalyzing shark, ray, and chimaera conservation. [PDF]
Conserv BiolFinucci B +10 more
europepmc +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
On the notion of false advertising: A reply to the letter by Theodore C. Chan and Gary M. Vilke on our article "Studying asphyxiation in the lab: the role of experimental evidence in cause-of-death inquiry". [PDF]
Hist Philos Life SciFischer E, Jukola S.
europepmc +1 more source
Revista Habanera de Ciencias Médicas: una mirada desde la Cienciometría
Revista Habanera de Ciencias MédicasRay Valdés Balbín +6 more
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Global scientific production on gamification in medical education: A bibliometric exploration. [PDF]
J Educ Health PromotBarja-Ore J +4 more
europepmc +1 more source