Results 211 to 220 of about 4,987 (254)
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[The role of citicoline in glaucoma].
Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 2021In recent years, many experimental and clinical studies have shown that in glaucoma, neuronal degeneration occurs not only at the level of the retina and optic nerve, but also along the entire visual pathway and the brain.This article presents the neuroprotective effects of citicoline and their mechanisms in glaucoma disease.The relevance of citicoline
Anselm G M, Jünemann +2 more
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Citicoline Preclinical and Clinical Update 2009–2010 [PDF]
Stroke, 2011 Citicoline is a neuroprotectant and neurorestorative drug that is used in the treatment of acute ischemic stroke in some countries. The research with this compound continues. In this review, we focus on the latest publications or communications or both and on the major ongoing experimental and clinical projects involving citicoline in stroke recovery.
Antoni Dávalos
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An Overview of Combination Treatment with Citicoline in Dementia
Reviews on Recent Clinical Trials, 2022Introduction: The present article reports an overview of the studies about combination treatment with citicoline of Alzheimer’s (AD) and mixed dementia (MD). Methods: A Medline search was carried out by using the keywords Alzheimer’s dementia, mixed dementia, older people, treatment with citicoline, memantine, and acetylcholinesterase inhibitors ...
Pietro Gareri +2 more
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Membrane Stabilizer: Citicoline
Current Medical Research and Opinion, 2002Brain ischaemia leads to a cascade of biochemical events, many of which ultimately cause cell membrane injury. Therefore, measures aimed at protecting neuronal membranes could be useful treatment strategies following stroke. Citicoline (cytidine-5-diphosphocholine; CDP-choline) is a naturally occurring nucleotide derivative that may reduce central ...
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Pharmacodynamics of citicoline relevant to the treatment of glaucoma
Journal of Neuroscience Research, 2001AbstractCiticoline (exogenous CDP‐choline) is a nontoxic and well‐tolerated drug used in pharmacotherapy of brain insufficiency and some other neurological disorders, such as stroke, brain trauma, and Parkinson's disease. A few reports indicate that citicoline treatment may also be beneficial in glaucoma.
Pawel, Grieb, Robert, Rejdak
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Citicoline Improves Verbal Memory in Aging
Archives of Neurology, 1996To test the verbal memory of older volunteers given citicoline.A randomized, double-blind, placebo-controlled, parallel group design was employed in the initial study. After data analysis, a subgroup was identified whose members had relatively inefficient memories. These subjects were recruited for a second study that used a crossover design.
P A, Spiers +4 more
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Efficacy of citicoline as an acute stroke treatment
Expert Opinion on Pharmacotherapy, 2009Citicoline (cytidine-5'-diphosphocholine or CDP-choline) is a precursor essential for the synthesis of phosphatidylcholine, one of the cell membrane components that is degraded during cerebral ischemia to free fatty acids and free radicals. Animal studies suggest that citicoline may protect cell membranes by accelerating resynthesis of phospholipids ...
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