Results 21 to 30 of about 31,300 (206)

Citoquinas: de fieles aliadas a temibles enemigas [PDF]

, 2011
Carrasco Otero, Librado
core   +2 more sources

Cytokine transcriptome profiling in acute experimental canine atopic dermatitis skin lesions after IL‐31 inhibition with lokivetmab

Veterinary Dermatology, Volume 34, Issue 4, Page 327-338, August 2023., 2023
Background – The caninised monoclonal antibody lokivetmab (LKV), directed at interleukin (IL)‐31, is very effective at controlling pruritus in most dogs with atopic dermatitis (AD). However, evidence exists that IL‐31 is not required for the induction of acute allergic skin inflammation, which might explain why this treatment is less efficacious in ...
Chie Tamamoto‐Mochizuki, Natalie Crawford, Jordan M. Eder, Andrea J. Gonzales, Thierry Olivry   +4 more
wiley   +1 more source

The effect of a mixed cannabidiol and cannabidiolic acid based oil on client‐owned dogs with atopic dermatitis

Veterinary Dermatology, Volume 33, Issue 4, Page 329-e77, August 2022., 2022
Background– Cannabidiol (CBD) and cannabidiolic acid (CBDA) are reported to have antinociceptive, immunomodulatory and anti‐inflammatory actions. Objectives – To determine if CBD/CBDA is an effective therapy for canine atopic dermatitis (cAD). Conclusions and clinical relevance – Cannabidiol/CBDA as an adjunct therapy decreased pruritus, and not skin ...
Melissa Loewinger, Joseph J. Wakshlag, Daniel Bowden, Jeanine Peters‐Kennedy, Andrew Rosenberg   +4 more
wiley   +1 more source

Altered plasma cytokines in dogs with atopic dermatitis

Veterinary Dermatology, Volume 33, Issue 2, Page 131-e38, April 2022., 2022
Background – Canine (Canis lupus familiaris) atopic dermatitis (AD) shares similar clinical signs to human AD. The abnormal immune response of AD is orchestrated by T lymphocytes, and may include variable involvement of cytokines, Regulatory T (Treg) cells, eosinophils, mast cells and other immune components.
Hamutal Mazrier, Linda J. Vogelnest, Rosanne M. Taylor, Peter Williamson   +3 more
wiley   +1 more source

Onset and duration of action of lokivetmab in a canine model of IL‐31 induced pruritus

Veterinary Dermatology, Volume 32, Issue 6, Page 681-e182, December 2021., 2021
Onset of antipruritic action of lokivetmab in dogs. Laboratory‐bred beagle dogs were dosed subcutaneously with either placebo or lokivetmab at 2.0 mg/kg on Day (D) 0. Approximately 2.5 h post‐dosing, pruritus was induced using canine interleukin (IL)‐31. Animals were observed for pruritic behaviours for a total of 2 h (3–5 h post‐treatment with placebo
Timothy J. Fleck, Lori R. Norris, Sean Mahabir, Rodney R. Walters, Olivier Martinon, Steven A. Dunham, Andrea J. Gonzales   +6 more
wiley   +1 more source

Immunopathogenesis and immunotherapy of Culicoides hypersensitivity in horses: an update

Veterinary Dermatology, Volume 32, Issue 6, Page 579-e156, December 2021., 2021
Culicoides hypersensitivity (CH) is a strongly pruritic dermatitis of horses, characterised histologically by mixed perivascular to diffuse cellular infiltrates of mononuclear cells and eosinophils, and caused by helper T cell (Th)2, immunoglobulin (Ig)E‐mediated reactions to antigens present in the saliva of biting Culicoides midges.
Eliane Marti, Ella N. Novotny, Iva Cvitas, Anja Ziegler, A. Douglas Wilson, Sigurbjörg Torsteinsdottir, Antonia Fettelschoss‐Gabriel, Sigridur Jonsdottir   +7 more
wiley   +1 more source

Immunopathogenesis of the feline atopic syndrome

Veterinary Dermatology, Volume 32, Issue 1, Page 13-e4, February 2021., 2021
Résumé Contexte Les maladies félines supposées d’origine allergique avec des phénotypes cliniques semblables, peuvent avoir de nombreuses pathogénies différentes sous jacentes. Le phénotype clinque, l’étiologie précise et l’immunopathogénie sous jacente doivent tous être considérés si des avancées veulent être faites dans ces domaines négligés de la ...
Richard Halliwell, Frane Banovic, Ralf S. Mueller, Thierry Olivry   +3 more
wiley   +1 more source

Tormenta de citoquinas: reacción adversa inhabitual por rituximab. Caso clínico [PDF]

Revista médica de Chile, 2017
Rituximab is a plausible alternative first-line treatment of ANCA-associated vasculitis. Adverse effects related to its infusion are common and usually have a benign course. However, there have been reports of refractory cardiogenic shock simulating septic shock. We report an 81-year-old male with the diagnosis of ANCA associated vasculitis.
Estefanía Palma, Vicente González, Daniela Grünholz, María Landaeta, María Mallea, José Pérez, Tomás Armstrong   +6 more
openaire   +3 more sources

Citoquinas en tuberculosis

Iatreia, 1997
La tuberculosis continúa siendo un modelo inmunológico para estudiar las infecciones intracelulares. Entenderlos complejos mecanismos de interacción de la micobacteria con el sistema inmune del hospedero permitirá un manejo más racional de los fenómenos clínicos que se presentan en la enfermedad.
García Moreno, Luis Fernando, Rojas López, Mauricio, Arias Pineda, Mauricio Alberto, Zabaleta Blanquicet, Jovany, Rodríguez Ospina, Jaime Ivan, París Ángel, Sara Claudia, Barrera Robledo, Luis Fernando   +6 more
openaire   +2 more sources

Revisión bibliográfica: tormenta de citoquinas producida por COVID-19

Investigación y Desarrollo, 2022
La infección por COVID-19 se ha convertido en un problema mundial de salud pública. La mortalidad potencial que representa, ha llevado a la investigación de su fisiopatología y la afectación a nivel celular, además la infección se puede complicar con el desarrollo de insuficiencia respiratoria, shock séptico, tromboembolismo, insuficiencia renal aguda,
Erick Fernández Jiménez, Cristian Silva Espinoza   +1 more
openaire   +1 more source