Results 181 to 190 of about 540,533 (312)

Androgen Receptor‐Induced Lactoferrin Accelerates Prostate Tumorigenesis Through Modulating Ferroptosis

Advanced Science, EarlyView.
This study demonstrates that transcription factor androgen receptor (AR) directly binds the LF promoter, driving lactoferrin overexpression to promote ferritin (FTH1/FTL) upregulation and inhibit p53‐ALOX12‐mediated ferroptosis in prostate cancer. Lactoferrin could be a new potential therapeutic target in prostate cancer.
Can Liu, Qiu Peng, Xiaoyue Zhang, Zhengshuo Li, Yangge Wu, Yuqing Wen, Run Zheng, Shuanglong Wu, Chenfei Zhou, Zhengyu Hu, Lanjun Shu, Xinyi Ma, Qiuyang Li, Ya Ma, Chunlin Ou, Ming Zhao, Songqing Fan, Lingyu Wei, Jian Ma   +18 more
wiley   +1 more source

Caffeine citrate increases ciliary beat frequency in human respiratory epithelial cells. [PDF]

Mol Cell Pediatr
Cindrić S, Bodenbeck L, Hjeij R, Loges NT, Edelbusch C, George S, Pennekamp P, Rieger-Fackeldey E, Omran H.   +8 more
europepmc   +1 more source

HNRNPU K181 Lactylation Drives Cervical Cancer Growth by Upregulating PHGDH and Reprogramming Serine Metabolism

Advanced Science, EarlyView.
Lactate in cervical cancer induces HNRNPU K181 lactylation, opposed by NAA50‐mediated acetylation and suppressed by Pazopanib. This lactylation enhances HNRNPU binding to PHGDH pre‐mRNA exon 1, maintaining exon 1‐containing transcripts and mRNA stability, thereby activating serine metabolism.
Chang Zhang, Qingfei Meng, Hui Jiao, Huixin Liu, Xiangchao Wang, Honglan Zhou, Yishu Wang   +6 more
wiley   +1 more source

Comparison of pre-analytical properties of blood collection systems for the diagnosis of diabetes mellitus. [PDF]

Pract Lab Med
Flindt J, Radziewitz M, Müller A, Harnack S, Schwarz A.   +4 more
europepmc   +1 more source

Antimicrobial effect of buffered sodium citrate (BSC) on foodborne pathogens in liquid media and ground beef

, 2010
The antimicrobial effects of a commercially available, buffered sodium citrate (BSC) were evaluated for the reduction of total aerobic bacteria count, Salmonella Typhimurium, Escherichia coli O157:H7, Listeria monocytogenes and Staphylococcus aureus in a
Fung, Daniel Y. C., Ryu, Si Hyun
core  

TSPYL5 Promotes Triple‐Negative Breast Cancer Metastasis by Antagonizing USP10‐Mediated PTEN Stabilization to Unleash a ZEB1‐Dependent EMT Program

Advanced Science, EarlyView.
The hyperactivation of PI3K/AKT signaling in PTEN wild‐type triple‐negative breast cancer represents a clinical paradox. We delineate a novel post‐translational regulatory axis wherein the oncogene TSPYL5 competitively antagonizes the deubiquitinase USP10.
Jiaying Shi, Ming Yi, Shengyu Xie, Zhaokun Wang, Xinyue Zhang, Yangwei Zhang, Rui Tang, Yuan Yang, Yunqiang Liu   +8 more
wiley   +1 more source

Original research a real-world study of adverse events of nafamostat mesylate and sodium citrate based on the world health organization-VigiAccess database. [PDF]

Front Pharmacol
Xu M, Wang Z, Yu B.
europepmc   +1 more source

PSMA8‐Containing 20S Proteasome Regulates Spermiogenesis and Male Fertility

Advanced Science, EarlyView.
PSMA8 assembles s20S proteasome that degrades specific substrates in elongating spermatids. Degradation of s20S‐substrates activates translation of FXR1‐target mRNAs, which are essential for mitochondrial sheath formation and sperm morphogenesis.
Huiwen Cao, Qianting Zhang, Wei Xu, Anxuan Fang, Haomang Xu, Cheng Qiu, Lugeng He, Chao Yu   +7 more
wiley   +1 more source

Efficacy and safety of a novel 18 mmol/L sodium citrate hemofiltration solution in continuous renal replacement therapy for critically ill patients: a retrospective cohort study. [PDF]

Transl Androl Urol
Zhao PH, Liu AQ, Chen YL, Liu HN, Li Z, Zhang XL, Lu NF.   +6 more
europepmc   +1 more source

Comparison of Gallium-67 Citrate and Technetium-99m Tetrofosmin Scan to Detect Hodgkin's Disease

, 2009
Objective: The purpose of this study was to compare the usefulness of gallium-67 citrate (Ga-67) and technetium-99m tetrofosmin (Tc-TF) scan to detect Hodgkin's disease (HD).
顏若芳, Liu, Feng-Yuan; Shiau, Yu-Chien; Yen, Ruoh-Fang; Wang, Jhi-Joung; Ho, Shung-Tai; Kao, Chia-Hung   +1 more
core