Results 31 to 40 of about 3,407,529 (287)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Assessing Walkability in Sulaimani City Center

open access: yesKurdistan Journal of Applied Research, 2020
Walkability within urban design and planning context refers to urban environments that are friendly and supportive for the pedestrian. Walkable environments offer many economic, social, health, and environmental benefits and contribute to UN Sustainable ...
Roza Abdullatif Radha   +2 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

A Company Profile for Ibis Surabaya City Center Hotel [PDF]

open access: yes, 2015
Company profile is a description of the company history, resources, structure, performance, and reputation. Therefore, company profile is very important for the hotel and it also plays an important role for business communication because it provides the ...
Gunawan, S. (Samuel)   +1 more
core  

Critiquing the Center: The Role of Tutor Evaluations in an Open Admissions Writing Center [PDF]

open access: yes, 2014
Though created to give its inhabitants the feeling of comfort, structure, and control, suburbia has been co-opted by postmodernists seeking to crack its modernist façade to reveal the hybridity, fragmentation, and hegemony at its commodified heart ...
Burns, William
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Housing Booms and City Centers [PDF]

open access: yesAmerican Economic Review, 2012
Popular discussions often treat the great housing boom of the 1996-2006 period as if it were a national phenomenon with similar impacts across locales, but across metropolitan areas, price growth was dramatically higher in warmer, less educated cities with less initial density and higher initial housing values.
Edward L. Glaeser   +2 more
openaire   +3 more sources

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

Evaluation of Yalova City Center and Çiftlikköy District in Terms of Vertical Garden

open access: yesDüzce University Faculty of Forestry Journal of Forestry, 2021
This study was conducted to specify the vertical gardens and potential areas where vertical gardens could be established in Yalova City Center and Çiftlikköy District between October 2020 and May 2021.
Özgür Kahraman, Doğukan Erman
doaj  

Forms and functions of market squares in small towns of lower Silesia/Mažų žemutinės Silezijos miestelių formos ir funkcijų tyrimas

open access: yesJournal of Architecture and Urbanism, 2008
In the paper market squares in small towns of Lower Silesia region are presented, their area does not exceed 1 ha. For the present work 15 localities were selected: 10 towns and 5 villages which formerly had civic rights.
Zuzanna Borcz   +1 more
doaj   +1 more source

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