Results 41 to 50 of about 3,407,529 (287)

Air Quality Issues and Settlement Suitability Analysis in Iğdır Central District

open access: yesCoğrafya Dergisi, 2023
Air pollution can be a concern during certain seasons, specifically in autumn and winter, in the city center of Iğdır owing to the city’s geomorphological and climatological features.
Mücahit Çoşkun   +3 more
doaj   +1 more source

Investigating the Magnitude and Range of the Urban Heat Island within Gettysburg, Pennsylvania [PDF]

open access: yes, 2017
Cities experience UHIs due to the thermal properties (albedo, thermal emittance, radiative flux, and heat capacity) of human-made substances and urban geometry.
Thompson, Samuel S., Wilkins, Rachel A.
core   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

PEMBATASAN PERKEMBANGAN PERMUKIMAN KAWASAN PINGGIRAN SEBAGAI UPAYA PENGENDALIAN PERKEMBANGAN KOTA SEMARANG

open access: yesTataloka, 2017
The need to settle is a basic need of people that must be fulfilled. The weakness of law enforcement and public awareness on the spatial planning implicate the emergence of settlement areas in various locations that are less suitable for its allocation ...
Bitta Pigawati   +2 more
doaj   +1 more source

Meneropong Morfologi Kota Pekanbaru pada Era Kolonial Belanda (1919-1942)

open access: yesAnalisis Sejarah, 2023
This study discusses the morphology changes of Pekanbaru City during the two decades of the Dutch colonial era (1919-1942).  This study had used historical research methods with a city morphology perspective.
Sabrina Sabrina, Zulqaiyyim Zulqaiyyim
doaj   +1 more source

Emergency Preparedness for Older People [PDF]

open access: yes, 2003
After the 9/11 World Trade Center attacks, a large population of older persona and people with disabilities living near the disaster area were left stranded in their homes without assistance.
Nora O'Brien
core  

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

Benchmarking Diversity: A First Look at New York City Foundations and Nonprofits [PDF]

open access: yes, 2009
New York City foundations and nonprofit organizations have racially diverse staffs, according to a new report by Philanthropy New York and the Foundation Center, but this diversity decreases at higher levels of seniority.
Brielle Bryan   +2 more
core  

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

The Entrance to Trabzon From East Gate: Tabakhane and Ortahisar

open access: yesIconarp International Journal of Architecture and Planning, 2017
The city of Trabzon, was established on a plenary hillside which remains in between Tabakhane and Zağnos valleys horizontally. In resources, it is mentioned that the first usage of the city’s name was “Trapezus” which means “table” and this usage was a ...
Neva Gerçek Atalay, Bahar Karakaş
doaj   +3 more sources

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