Results 51 to 60 of about 3,407,529 (287)
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Historical center and present city
In_Bo, 2010 La nostra regione nel passato è stata considerata un vero e proprio laboratorio per l’intervento nei centri storici, dall’esperienza pilota del Piano PEEP di Bologna alla successiva applicazione generalizzata della “disciplina particolareggiata ...
Carlo Monti
doaj +1 more source
Characteristics and Influencing Factors of Land Use Transition in Haikou City During 2009-2018
Shuitu baochi tongbao, 2022 [Objective] The spatial distribution characteristics and impacts of land use transition in Haikou City were quantitatively identified in order to provide a scientific reference for land and space planning of Haikou City.
Wang Ting, Wei Shichuan
doaj +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Street Vendors Unite! Recommendations for Improving the Regulations on Street Vending in New York City [PDF]
, 2009 Both the Street Vendor Project of the Urban Justice Center and Local 169 of the Union of Needle trades, Industrial and Textile Employees (UNITE), have committed resources and time on behalf of the city's vendors in an attempt to break the bureaucratic ...
core
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
The new ideal : reshaping Schererville [PDF]
, 2010 Schererville, Indiana could be considered a suburb of Chicago due to its proximity to major highways leading there and the number of people who live there and commute to the city. But Schererville still has an identity of its own.
DeVries, Jessica L.
core +1 more source
FEBS Open Bio, EarlyView.A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li +6 more
wiley +1 more source
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source