Results 51 to 60 of about 180,987 (265)
Urban climate action plans (UCAPs) guide cities in identifying key climate risks and in addressing climate change. Designed to guide urban transformation over decades through near-term and long-term actions reducing emissions and/or adapting to the ...
Niklas Wagner, Minal Pathak
doaj +1 more source
With the unprecedented technological advances witnessed in the last two decades, more devices are connected to the Internet, forming what is called the Internet of Things (IoT).
Raouf Abozariba +5 more
doaj +1 more source
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant +7 more
wiley +1 more source
From Local Action to Global Influence: How Cities Shape Governance in a Polycentric World
Municipal leadership has become increasingly central to addressing global challenges such as war-related displacement, migration governance, and climate change, reflecting a broader shift toward polycentric and networked forms of multilateralism.
Colleen Thouez, Raphaela Schweiger
doaj +1 more source
I-sieve: An Inline High Performance Deduplication System Used in Cloud Storage
Data deduplication is an emerging and widely employed method for current storage systems. As this technology is gradually applied in inline scenarios such as with virtual machines and cloud storage systems, this study proposes a novel deduplication ...
Jibin Wang +5 more
doaj +1 more source
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo +7 more
wiley +1 more source
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
We demonstrate transmission of a 200-Gb/s superchannel over 3-km single-mode optical fiber (SMF) targeting intra-data center interconnect applications using a novel single-section quantum-well passive-mode-locked laser that generates an optical frequency
Tam N. Huynh +11 more
doaj +1 more source
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho +4 more
wiley +1 more source

