Results 161 to 170 of about 2,059,614 (360)

Combining PIM‐2 and PARP1 Inhibitors Induces MICA Expression on Multiple Myeloma Cells to Activate NK Cells through NKG2D Binding

open access: yesAdvanced Science, EarlyView.
The findings suggest that the combination of PIM‐2 and PARP1 inhibitors can induce MICA expression on MM cells, thereby activating NK cells through NKG2D binding. This process may restore NK cell function and serve as a potential therapeutic approach for MM patients. Abstract While immunogenic death in tumor cells activates specific anti‐tumor T cells,
Zhaoyun Liu   +6 more
wiley   +1 more source

Wearable Bioelectronics for Home‐Based Monitoring and Treatment of Muscle Atrophy

open access: yesAdvanced Science, EarlyView.
As an inevitable disease, muscle atrophy has received more attention. Because the factors that induce this disease are diverse, achieving a complete cure is still impossible. Wearable bioelectronics provides a more comfortable, low‐cost, and efficient way of home care for the monitoring and treatment of muscle atrophy. Therefore, this review summarizes
Shuai Zhang   +4 more
wiley   +1 more source

Mechanical Metamaterial‐Based Structure with Magnetically Controlled Nonreversibility and Nonreciprocity for Programmable Locomotion

open access: yesAdvanced Science, EarlyView.
A magneto‐mechanical metamaterial‐based structure that simultaneously exhibits programmable nonreversibility and nonreciprocity. These cause substantial transitions in static mechanical properties, such as Poisson's ratio and stiffness, leading to stark changes in energy absorption.
Krzysztof K. Dudek   +3 more
wiley   +1 more source

High‐Performance Rechargeable Lithium‐Chlorine Batteries with ALD Conformal Starburst Porous Graphene Positive Electrodes

open access: yesAdvanced Science, EarlyView.
An Al2O3‐skinned starburst porous graphene with conformal metasurfaces is crafted from a hierarchical porous graphene with high surface pore curvature by PTFE microemulsion skin effect, leveraging subsequent atomic layer deposition of Al2O3 groups. The scalable heterostructured cathode features superhydrophilicity, effective adsorption, fast kinetics ...
Zhuo Yang   +10 more
wiley   +1 more source

Mucociliary Clearance Inspired Nanozyme‐centric Hydrogel Composites for Integrated Bacterial Detection

open access: yesAdvanced Science, EarlyView.
Inspired by human pulmonary cilia and their mucus defend against bacteria, nanozyme‐centric hydrogel networks have been assembled into nanowires, combining the rapid penetration capability of the nanowire arrays with the adhesion and detection functions of the nanozyme‐centric hydrogel networks.
Zhaoling Tan   +4 more
wiley   +1 more source

ALBANIAN LAW ON CITY PLANNING: CRITICAL SUMMARY OF ITS MAJOR PROVISIONS [PDF]

open access: yes
This paper includes, as an annex, Law No. 7693, "On Urban Planning," from the People's Assembly of the Republic of Albania. Conceptually, this law has five major parts: (1) planning generally, (2) getting construction permission, (3) special provisions ...
Craig, William, Jacobs, Harvey M.
core   +1 more source

Urban Environmental Planning in Greek Cities - The response of medium sized Greek cities, the case of Volos [PDF]

open access: yes
The city is a vital sum of functions, of human actions, of resources and of a built and physical environment. The sustainability of cities is relatively a new area of interest, especially for the Greek cities.
Eftychia Antoniou
core  

HPD is an RNA‐Binding Protein Sustaining Ovarian Cancer Cell Glycolysis, Tumor Growth, and Drug Resistance

open access: yesAdvanced Science, EarlyView.
HPD is identified as an RNA‐binding protein that promotes mRNA translation by binding to RRACH motifs via its double‐stranded RNA‐binding domains. This RNA‐binding activity critically sustains glycolysis in ovarian cancer cells. Disrupting HPD's RNA‐binding function effectively suppresses tumor growth and enhances therapeutic sensitivity, highlighting ...
Fei Xie   +21 more
wiley   +1 more source

A city planning primer by the advisory committee on zoning appointed by Secretary Hoover

open access: bronze, 1926
Charles B. Ball   +10 more
openalex   +1 more source

Copper‐Based Nanotubes That Enhance Starvation Therapy Through Cuproptosis for Synergistic Cancer Treatment

open access: yesAdvanced Science, EarlyView.
We designed a copper‐based nanotube (NT) with copper ionophores to induce enhanced cuproptosis. In combination with starvation therapy, the NT significantly inhibited energy metabolism in HCC cells. Our results show that the depletion of GSH by Cu2+ intensified oxidative stress and cuproptosis, resulting in ROS generation and DLAT aggregation ...
Xuan Han   +8 more
wiley   +1 more source

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