Results 51 to 60 of about 7,967,130 (268)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Ray City Council Meeting Minutes, 1968 - 1982

, 1982
Ray City Council Meeting Minutes, 1968 - 1982. 1 electronic record (PDF), 89.3 MB (93,658,298 bytes).Ray City Council Meeting Minutes, 1968 - 1982. Ray City School. CA014-001: Ray City Community Library, 1952–1994 Series.
Ray City Community Library
core   +1 more source

Effect of city size on start-up lost time at signalized intersections [PDF]

Tehnika
In recent years, the degree of motorization and transport work have been expanding, while the development of infrastructure, road and street networks, has not followed their growth.
Nikolić Tijana A., Čelar Nikola Đ., Stanković Stamenka R.   +2 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Ray City Council Meeting Minutes, 1952 - 1967

, 1967
Ray City Council Meeting Minutes, 1952 - 1967. 1 electronic record (PDF), 175 MB (184,401,472 bytes).Ray City Council Meeting Minutes, 1952 - 1967. Ray City School. CA014-001: Ray City Community Library, 1952–1994 Series.
Ray City Community Library
core   +1 more source

A simple method to estimate the urban heat island intensity in data sets used for the simulation of the thermal behaviour of buildings

Meteorologische Zeitschrift, 2013
Test Reference Years (TRY) are data sets tailored for use in the context of simulations with respect to the thermal behaviour of buildings. They are based on measurements and observations from weather stations of the German Meteorological Service ...
Uwe Wienert, Frank Kreienkamp, Arne Spekat, Wolfgang Enke   +3 more
doaj   +1 more source

Theoretical study of the effect of ports in the formation of city systems

Journal of Shipping and Trade, 2022
This paper explores theoretically the formation of a system of cities in which ports affect the spatial location and the size of cities. We use a complex systems and economic geography approach to generate 2D cellular automata to simulate the formation ...
Igor Lugo, Gustavo Martínez-Mekler
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Dynamic Henry George Theorem and Optimal City Sizes

International Studies of Economics
The Henry George Theorem (HGT) in static models states that when a city has an optimal population size, aggregate urban differential land rents exactly cover costs of pure public goods. This paper extends the static HGT to dynamic settings.
Shihe Fu
doaj   +1 more source