Results 191 to 200 of about 515,423 (264)

Artificial Intelligence‐Guided Phenotypic Drug Repurposing Against Streptococcus pneumoniae

Advanced Science, EarlyView.
Integrated artificial intelligence (AI) ensembles identify highly potent repurposed drugs against Streptococcus pneumoniae. Prospective virtual screening of 6747 drugs uncovers nine active candidates, including thiostrepton. This drug exhibits low picomolar potency and bypasses established resistance in multidrug‐resistant strains, demonstrating an ...
Joshua S. Fitch, Muhammad D. Ariadi, Min Jung Kwun, Leonie Howells, Saiveth Hernandez‐Hernandez, Nicholas J. Croucher, Pedro J. Ballester   +6 more
wiley   +1 more source

Effects of Habitat Types on Pollinators and Seasonal Variations in Plant-Insect Pollination Networks in Nanchong, China. [PDF]

Insects
Wang Q, Zou Y, Zhou X, Zhang J, Li X.
europepmc   +1 more source

Engineering Ultrastable Intrinsic Radicals: Graphene Quantum Dots With NIR‐II Emission for Dynamic Deep‐Tissue Bioimaging

Advanced Science, EarlyView.
Stable radicals are attractive for photonic and quantum information technologies but are often limited by instability. We stabilize intrinsic radicals in graphene quantum dots via 2D polymerization of perylene derivatives, where bilayer defect confinement suppresses quenching (100–500 K).
Qin Xu, Yijie Hou, Bingzhe Wang, Tesen Zhang, Yupeng Liu, Shuaiqi Li, Maohua Chen, Guichuan Xing, Dongbo Guo, Songnan Qu   +9 more
wiley   +1 more source

Industrial green transformation efficiency and its driving factors in resource-based cities: the case of the Yellow River Basin. [PDF]

Sci Rep
Yuchun Y, Jiayao L.
europepmc   +1 more source

Multi‐Scale Bionic Structure Constructs Biomass Flame‐Retardant Thermal Insulation Foam Material

Advanced Science, EarlyView.
Inspired by mussel adhesion and hierarchical brick‐and‐mortar architectures, a cellulose‐based biomimetic foam is constructed by anchoring bentonite nanosheets onto a polydopamine‐decorated cellulose nanofiber network. The resulting foam combines low thermal conductivity with intrinsic flame retardancy and full biodegradability, presenting a ...
Jianming Liao, Lijun Fan, Yunyuan Dong, Xuyu Bao, Xiaobin Chen, Qifu Zheng, Guanqing Zhang, Shen Wang, Wei Chen, Min Zhang, Shuaiming He   +10 more
wiley   +1 more source

Structural Entropy, Modal Diversity Entropy, and Accessibility Differentiation: A Study of the Western China-Central Asia Cross-Border Multimodal Transportation Network. [PDF]

Entropy (Basel)
Sun R, Xin Y, Shao Y, Ju P.
europepmc   +1 more source

circZNF148 Drives Glucose Metabolism Reprogramming to Enhance Metastasis and Immune Evasion via HK1 Stabilization in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
CircZNF148 stabilizes HK1 through deubiquitinase recruitment, thereby enhancing glycolysis and lactate production. Elevated lactate promotes PD‑L1 lactylation and membrane accumulation while suppressing CD8+ T‐cell cytotoxicity, collectively facilitating immune evasion and malignant progression in TNBC.
Yuhan Jin, Wenjing Zhao, Lei Wang, Jianing Wang, Keying Zhao, Dan Luo, Yifei Wang, Yuxia Yang, Jingze Yang, Yaming Li, Tong Chen, Dianwen Han, Zekun Wang, Xiaoyan Li, Bing Chen, Lijuan Wang, Yiran Liang, Qifeng Yang   +17 more
wiley   +1 more source

Psychometric properties of the Person-Centered Palliative Care Nursing Instrument (PPCNI): validity and reliability study. [PDF]

BMC Palliat Care
Yılmaz MŞ, Karaca A, Köse S, Ürkmez DÖ, Yıldırım G.   +4 more
europepmc   +1 more source