Results 31 to 40 of about 492,148 (264)

Structure of the Diphtheria Toxin at Acidic pH: Implications for the Conformational Switching of the Translocation Domain

open access: yesToxins, 2020
Diphtheria toxin, an exotoxin secreted by Corynebacterium that causes disease in humans by inhibiting protein synthesis, enters the cell via receptor-mediated endocytosis. The subsequent endosomal acidification triggers a series of conformational changes,
Mykola V. Rodnin   +5 more
doaj   +1 more source

Influence of molecular packing on the color-tunable emissive behavior of viologen derivatives

open access: yesResults in Chemistry, 2022
Color-tunable organic solid-state luminescent materials have received increasing attention owing to their potential applications in displays, imaging, encryption, etc.
Guo-Chao Li   +5 more
doaj   +1 more source

Publisher Correction: Molecular dynamics of the histamine H3 membrane receptor reveals different mechanisms of GPCR signal transduction

open access: yesScientific Reports, 2021
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Leonardo David Herrera-Zúñiga   +8 more
doaj   +1 more source

Therapeutic Apheresis in Nigeria: A Multi‐Center Summary of Abstracts From the Inaugural Nigerian Society for Apheresis Scientific Meeting

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Therapeutic apheresis (TA) is an established treatment modality for hematologic, neurologic, and immunologic disorders, yet access remains severely limited in sub‐Saharan Africa. Donor apheresis, including platelet apheresis collection from healthy donors, represents an important complementary modality supporting blood product ...
Nosa Bazuaye   +33 more
wiley   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin   +2 more
wiley   +1 more source

The architectural-ensemble problem in the construction of public buildings in Kazan in the late 1960s–1980s and the principles of their placement

open access: yesАрхитектон
The article discusses the development of city structure and principles public building placement in it. The location of Kazan on a hilly terraced terrain ensures visual perception of its central part, and most public buildings contribute to the ...
Zakirova Tatyana R.
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Fabrication of h-BN solar-blind ultraviolet detectors by RF magnetron sputtering

open access: yesNext Materials
Hexagonal boron nitride (h-BN) has become a popular material in solar-blind ultraviolet (SBUV) detection due to its ultra-wide bandgap, high optical absorption coefficient, high breakdown field strength and high thermal conductivity.
Cheng Wu   +5 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

City center organization and its influence on the city structure [PDF]

open access: yesFacta Universitatis. Series: Architecture and Civil Engineering, 2004
A city center is a starting and end point of numerous and various movements of a city, so called "basic paths focus". Therefore, it is strained by the tensions of the centrifugal and centripetal courses of the city and its denizens.
Mitković Petar, Dinić Milena
doaj   +1 more source

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