Results 121 to 130 of about 1,934,499 (254)
A multiscale Bayesian optimization framework for process and material codesign
Abstract The simultaneous design of processes and enabling materials such as solvents, catalysts, and adsorbents is challenging because molecular‐ and process‐level decisions are strongly interdependent. Sequential approaches often yield suboptimal results since improvements in material properties may not translate into superior process performance. We
Michael Baldea
wiley +1 more source
Abstract This work presents the optimization of cell cultivation for monoclonal antibody (mAb) production. We developed a hybrid model describing the effects of multiple process variables on antibody productivity and impurity generation. An automated platform with 12 × 250 mL bioreactors was set up.
Kosuke Nemoto +6 more
wiley +1 more source
The EU-Mercosur agreement: towards integrated climate policy? Egmont European Policy Brief No. 57 November 2019 [PDF]
The recently signed EU-Mercosur agreement has met with criticism from civil society, farmers and politicians around the EU. These criticisms have been amplified by recent forest fires in the Amazon.
Colli, Francesca
core
Abstract Three instruments–Raman spectroscopy, attenuated total reflectance–Fourier transform infrared spectroscopy, and focused beam reflectance measurement–were used to detect sensor faults, mixing faults, and unanticipated chemistry in a system of multicomponent slurries.
Steven H. Crouse +2 more
wiley +1 more source
Trust‐region filter algorithms utilizing Hessian information for gray‐box optimization
Abstract Optimizing industrial processes often involves gray‐box models that couple algebraic glass‐box equations with black‐box components lacking analytic derivatives. Such systems challenge derivative‐based solvers. The classical trust‐region filter (TRF) algorithm provides a robust framework but requires extensive parameter tuning and numerous ...
Gul Hameed +4 more
wiley +1 more source
Abstract Antimicrobial resistance has become a major threat to human health, particularly for Gram‐negative bacteria such as Acinetobacter baumannii and Klebsiella pneumoniae. Disruption of membrane integrity is regarded as a promising antimicrobial strategy that does not induce distinct drug resistance, while increasing the internalization of drug ...
Lei Hao +10 more
wiley +1 more source
Recent Trends in Antitrust Civil Action Damage Determinations [PDF]
Weinberg, David B.
core +2 more sources
Final Report: Conference in Paris on 29 June 2012 - How to Communicate About the European Citizens' Initiative? [PDF]
The 29 June 2012 conference, entitled "How to communicate about the European Citizens' Initiative?" falls within the ambit of a project launched by our partner ECAS (European Citizen Action Service).
core
3D investigation and modeling of the geometric effects on porosity in packed beds
Abstract In porous beds, physical boundaries restrict particle arrangement, leading to inhomogeneous porosity. This paper reports on the porosity profiles that are the result of geometric effects on monodisperse packed beds in cylindrical and cubic arrangements. Special focus is given to the influence of edges and corners in cubic geometries.
Bastian Oldach +3 more
wiley +1 more source
A trust‐region funnel algorithm for gray‐box optimization
Abstract Gray‐box optimization, where parts of optimization problems are represented by algebraic models while others are treated as black‐box models lacking analytic derivatives, remains a challenge. Trust‐region (TR) methods provide a robust framework for gray‐box problems through local reduced models (RMs) for black‐box components, but they are ...
Gul Hameed +4 more
wiley +1 more source

