Results 291 to 300 of about 1,673,815 (341)

Flux Sampling Suggests Metabolic Signatures of High Antibody‐Producing CHO Cells

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Chinese hamster ovary (CHO) cells remain the industry standard for producing numerous therapeutic proteins, particularly monoclonal antibodies (mAbs). However, achieving higher recombinant protein titers remains an ongoing challenge and a fundamental understanding of the cellular mechanism driving improved bioprocess performance remains ...
Kate E. Meeson   +9 more
wiley   +1 more source

Applications of muon absorption radiography to the fields of archaeology and civil engineering. [PDF]

open access: yesPhilos Trans A Math Phys Eng Sci, 2018
Saracino G   +8 more
europepmc   +1 more source

Physiology and Robustness of Yeasts Exposed to Dynamic pH and Glucose Environments

open access: yesBiotechnology and Bioengineering, EarlyView.
The authors investigated how three Saccharomyces cerevisiae strains respond to dynamic substrate and pH oscillations using dynamic microfluidic single‐cell cultivation (dMSCC) and intracellular biosensors. By combining performance and robustness analysis of selected intracellular parameters, growth and morphological analysis, the authors identified ...
Luca Torello Pianale   +3 more
wiley   +1 more source

Encapsulation of Fiber Optic Sensors in 3D Printed Packages for Use in Civil Engineering Applications: A Preliminary Study. [PDF]

open access: yesSensors (Basel), 2019
Scott R   +6 more
europepmc   +1 more source

Systematic Investigation of Impact of Antifoam and Extracellular Vesicles on Fouling of Hollow Fiber Filters in Intensified Perfusion Processes Highlights the Key Impact of Antifoam

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Ultra‐high cell density perfusion cultures are becoming increasingly attractive for biologics manufacturing due to their ability to boost productivity and offer a flexible manufacturing footprint. However, these intensified perfusion processes pose challenges, particularly concerning the performance of hollow fiber filters used as cell ...
Sri Ranganayaki Madabhushi   +6 more
wiley   +1 more source

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