Results 241 to 250 of about 1,195,414 (313)

Gaussian Processes for Predictive QSAR Modeling of Chromatographic Processes

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Chromatography is a key unit operation in the biopharmaceutical manufacturing process used for protein purification and polishing. Design and optimization of these processes are resource‐intensive resulting from the complex combinatorial design space.
Harini Narayanan, Douglas Nolan, Lijuan Li, Edward King, Andrew Fiordalis, David Benjamin Nickel, George Parks, J. Christopher Love   +7 more
wiley   +1 more source

Phenazine‐Based Synthetic Biology to Signal Between Cells and Electrodes

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Bioelectronic systems that enable seamless communication between electronic devices and living systems represent a transformative frontier in biotechnology. Among available methodologies, redox based signaling offers unique advantages due to its ubiquity in biology and compatibility with standard electrochemical equipment, expanding on ...
Eric VanArsdale, Monica Chu, Sally Wang, Divya Muthusamy, Eric Wold, Yi Liu, G. F. Payne, Tanya Tschirhart, W. E. Bentley   +8 more
wiley   +1 more source

Civil society and the (im)possibilities of algorithmic contestation in migration governance. [PDF]

Front Sociol
Eneva SA, Mora-Gámez F.
europepmc   +1 more source

Quantitative Analysis Reveals Hitchhiking Drives Polysorbate Hydrolase Persistence Via Host Cell Protein–Antibody Interactions

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Polysorbate‐degrading host cell proteins (HCPs) represent a critical challenge in the manufacturing of monoclonal antibody therapeutics due to their potential to persist during downstream processing. While their enzymatic activity has been characterized, the role of direct HCP‐mAb interactions, particularly those involving polysorbate ...
Melanie Maier, Lukas Griesinger, Matthias Franzreb, Simon Kluters   +3 more
wiley   +1 more source

Describing the roles of civil society organizations in sustaining adolescents' family planning programs in nine Asian and African countries. [PDF]

Contracept Reprod Med
Khuzaiyah S, Gondwe YG, Desireh GA, Bolaji M, Gomes RF, Hossen M, Chia KR, Andrianirina R, Fitriyani F, Kusuma NI, Tun HM.   +10 more
europepmc   +1 more source

Multimodal Chromatography in the Downstream Processing of mAb‐Based Products: Mechanisms, Strategies, and Applications

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Multimodal chromatography has emerged as a powerful tool for the purification of monoclonal antibodies (mAbs) and their derivatives—including antibody fragments (Fabs), Fc‐fusions, bispecific (BsAb), and antibody–drug conjugates (ADCs)—offering enhanced selectivity through the integration of ionic, hydrophobic, hydrogen‐bonding, and π–π ...
Amin Javidanbardan, Marco P․ C․ Marques, Ana M. Azevedo, Daniel G. Bracewell, Stephen Goldrick   +4 more
wiley   +1 more source

Enhancing collaboration between national TB programmes and researchers. [PDF]

IJTLD Open
Dall'Olio L, de Colombani P, Servello J, Gargioni G, Duarte R, Raviglione M.   +5 more
europepmc   +1 more source

Development and evaluation of a comprehensive Patient for Medication Safety (PFMS) intervention programme to improve participation in medication safety behaviours among older adults with chronic disease during hospital-to-home transition: a pilot randomized controlled trial. [PDF]

BMC Geriatr
Xu W, Lin X, Lai H, Ren Y, Peng S, Lin T.   +5 more
europepmc   +1 more source

Community-driven strategies for primary health care resilience in response to shocks in Latin America and the Caribbean: a scoping review and expert consultation. [PDF]

Lancet Reg Health Am
Houghton N, Bascolo E, Zavaleta C, Flores W, Kain MC, Vance Mafla CI, Haggerty J.   +6 more
europepmc   +1 more source