Results 161 to 170 of about 835,269 (296)

Addressing Small Data Challenges in Biopharmaceutical Development and Manufacturing: A Mini Review of Multi‐Fidelity Techniques

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT The growing demand for biopharmaceutical products reflects their effectiveness in medical treatments. However, developing new biopharmaceuticals remains a major bottleneck, often taking up to a decade before market approval. Machine learning (ML) models have the potential to accelerate this process, but their success depends on access to large
Mohammad Golzarijalal   +2 more
wiley   +1 more source

Dynamic, Unconstrained Optimization of Secreted Enzyme Production in Fed‐Batch Fermentation Using Reinforcement Learning

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Reinforcement learning (RL) has been used to control a wide range of dynamic processes, especially ones that are too complex to model well or have stochastic environmental perturbations. Fed‐batch fermentations are subject to changes in starting cell growth rates and process variations that can affect cell growth and secreted target production.
Sai Harish Uthravalli   +3 more
wiley   +1 more source

Roles of 2D halide perovskites in 2D/3D heterojunctions for high‐performance perovskite solar cells

open access: yesBulletin of the Korean Chemical Society, EarlyView.
This review establishes a design framework for two‐dimensional (2D)/three‐dimensional (3D) perovskite heterojunctions, redefining the 2D perovskite layer as an active semiconductor component. We classify 2D structures by spacer chemistry and analyze their roles within the heterojunction.
Seungmin Lee   +4 more
wiley   +1 more source

Strategic Innovation for Sustainability: A Conceptual Model Linking Digitalization, Social Dynamics, and Climate Change Mitigation

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT This study addresses a significant research gap in the literature by systematically reviewing and synthesizing the interplay between social dynamics, environmental changes, and organizational innovation. Although prior research has explored these dimensions in isolation, the integrative framework remains lacking.
Gagan Deep Sharma   +4 more
wiley   +1 more source

Navigating the ESG Paradox: Strategic Pathways Between Innovation and Washing Under Stakeholder Scrutiny

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT As firms increasingly incorporate environmental, social, and governance (ESG) concerns into their strategic agendas, stakeholder legitimacy—an audience‐conferred judgment of organizational appropriateness—has become pivotal. We theorize legitimacy as expanding a hybrid response portfolio in which firms may pursue substantive change (business ...
Min‐Jae Lee   +3 more
wiley   +1 more source

Rebound Effects in Circular Manufacturing: Overview of Potential Rebound Mechanisms Activated by Circular Strategies Across Key Business Processes

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT Circular economy (CE) is increasingly adopted by the manufacturing industry to decouple economic growth from environmental impacts by optimizing resource use and minimizing waste generation. Nevertheless, circular manufacturing often triggers systemic responses that diminish or offset their potential environmental gains, resulting in the so ...
Mariantonietta Ferrante   +2 more
wiley   +1 more source

Social movements are transformative agents for biodiversity conservation. [PDF]

open access: yesProc Natl Acad Sci U S A
Walter M   +6 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy