Results 221 to 230 of about 64,359 (278)
FEBS Open Bio, EarlyView.The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
Generative Artificial Intelligence in Academic Publishing: <i>A catalyst for transformation or a facilitator for further north-south divide?</i> [PDF]
Sultan Qaboos Univ Med JAl-Adawi S, Maddali MM.
europepmc +1 more source
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
FEBS Open Bio, EarlyView.Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
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Civilisations précolombiennes, civilisations du maïs
Annales. Histoire, Sciences Sociales, 1948Petite note, grande question. Il y a longtemps qu'aux Annales ce problème des « aliments de base » nous préoccupe. Mais sans que nous puissions toujours pousser à fond l'étude des conséquences politiques, sociales, artistiques qu'entraîne l'usage d'une nourriture particulière, adoptée, sur un vaste domaine, par des hommes de culture différenciée.
Febvre, Lucien +1 more
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Civilisational and anti-civilisational conflicts
2021In this article, the authors argue in favour of their principal thesis about anticivilizational conflicts, contending with the theses about the “clash of civilisations” presented by Samuel Huntington in 1996. Their goal is to identify a new paradigm and the modern implications of civilizational conflicts, or clashes of civilisations, as well as to ...
Miliša, Zlatko +2 more
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Civilisation japonaise et civilisation européenne
Annales. Histoire, Sciences Sociales, 1962L'historien qui cherche à reconstituer la genèse de la civilisation japonaise, a la surprise de trouver à chacun des éléments qui la composent et même aux plus typiques (vêtement, maison, temples, sports) une origine étrangère. Les domaines où les artistes japonais ont excellé furent ainsi fécondés par l'étranger.
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How to be Human: The Civilised and the Civilisable
2009Over the centuries, the concept of civilisation has changed and adapted to the historical context. The Greeks, Romans and Arabs associated the word ‘civilisation’, which derives from the Latin word civilis, to the urban environment and lifestyle. From a technical word, the word civilisation, as we shall see, has become part of a political discourse of ...
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