Results 241 to 250 of about 258,864 (309)

Prevalence of Chronic Kidney Disease Risk Factors in Rural Tanzania: Insights From a Community-Based Screening in Kilombero. [PDF]

Health Sci Rep
Lubomba W, Edward M, Justine J, Laizer Z, Pius A, Tibenderana J, Thomas C.   +6 more
europepmc   +1 more source

Toxicity Differences Between Microplastics and Nanoplastics in Organs: From Molecular Mechanisms to Potential Therapeutic Strategies

Med Research, EarlyView.
This review systematically compares the size‐dependent toxicity of microplastics and nanoplastics in the intestine, liver, kidney, lung, and brain. Particle size determines bioavailability, barrier penetration, and injury mechanisms. Because of their small size and high surface reactivity, NPs readily cross the intestinal epithelium and blood–brain ...
Yixian Cheng, Junjie Chen, Rui Fu, Jiawei Zhang, Jianguang Jia, Wei Wang, Zheng Zhang, Peng Zhang, Haosong Chen, Huake Cao, Gang Li, Weiwei Sheng, Ting Li, Bo Chen, Guodong Cao   +14 more
wiley   +1 more source

Managing Early-Stage Chronic Kidney Disease: A Qualitative Study of Patients' and Healthcare Professionals' Perspectives. [PDF]

Nurs Health Sci
Perdana M, Roberts J, Moffatt F, Blake H.   +3 more
europepmc   +1 more source

Hyperhomocysteinemia and Vitamin B Deficiency as Potential Aggravating Factors in Huntington's Disease: A Prospective Monocentric Study

Movement Disorders, EarlyView.
Abstract Background Although not confirmed, some studies have suggested that elevated homocysteine levels are common in patients with Huntington's disease (HD). Its clinical relevance remains unclear. Objectives We aimed to assess vitamin B and homocysteine levels in HD patients and explore the relationships among hyperhomocysteinemia, vitamin B ...
Salomé Puisieux, Elise Pourié, Céline Bonnet, Lucie Hopes, Solène Frismand, Myriam Bronner, Virginie Roth, Marion Wandzel, Natacha Sloboda, Laetitia Lambert, Abderrahim Oussalah, Amélia Julien, Irina Rotaru, Rosa‐Maria Guéant‐Rodriguez, Jean Louis Guéant, Carine Bossenmeyer‐Pourié, Mathilde Renaud   +16 more
wiley   +1 more source

Undiagnosed Chronic Kidney Disease, Outcomes, and Finerenone in Heart Failure: The FINEARTS-HF Randomized Clinical Trial.

JAMA Cardiol
Ostrominski JW, Mc Causland FR, Claggett BL, Desai AS, Jhund PS, Henderson A, Lam CSP, Senni M, Shah SJ, Voors AA, Zannad F, Pitt B, Amarante F, Brinker M, Schloemer P, Rohwedder K, McMurray JJV, Solomon SD, Vaduganathan M.   +18 more
europepmc   +1 more source

Multiparametric MRI for Early Chronic Kidney Disease Detection: Insights Into Renal Microcirculation. [PDF]

NMR Biomed
Zha T, Pan L, Yang Y, Du Y, Chen Y, Wen Q, Chen J, Jiang Z, Xing W.   +8 more
europepmc   +1 more source

Ursodeoxycholic Acid and Parkinson's Disease Risk: An Emulated Target Trial in UK Electronic Health Records

Movement Disorders, EarlyView.
Abstract Background Ursodeoxycholic acid (UDCA) has shown mitochondrial and neuroprotective effects and has been proposed as a treatment for Parkinson's disease (PD). However, population‐level evidence on its effect on PD risk is lacking. Objectives To compare the risk of incident PD among UDCA initiators versus matched non‐initiators within a ...
Chengsheng Ju, Anette Schrag, Camille Carroll, Xi Xiong, James Carpenter, Oliver Bandmann, Thomas Foltynie, Li Wei   +7 more
wiley   +1 more source

Transcriptional risk score for chronic kidney disease: relation to Alzheimer's disease. [PDF]

Alzheimers Dement
Pyun JM, Park YH, Hwang J, Kim S, Yi Y, Nho K, Alzheimer's Disease Neuroimaging Initiative.   +6 more
europepmc   +1 more source

Redefining CHI3L1: Therapeutic Opportunities at the Crossroads of Immune Suppression and Disease Progression

Medicinal Research Reviews, EarlyView.
ABSTRACT Chitinase‐3‐like‐1 (CHI3L1, also known as YKL‐40) has been recognized as a biomarker of inflammation and tissue remodeling and has now emerged as a pseudoenzymatic immune checkpoint. Recent structural, immunological, and translational studies redefine it as an active regulator of immune suppression rather than a passive disease marker. Despite
Kirti Upmanyu, Saurabh Upadhyay, Moustafa T. Gabr   +2 more
wiley   +1 more source

Beyond Kidney Function: A Neuro-Renal Perspective on Personalized Care in Pediatric Chronic Kidney Disease. [PDF]

Med Sci (Basel)
Manzar A, Tonkovic U, Mijuskovic S, Sic A, Altic A, Pavlovic J, Baralic M.   +6 more
europepmc   +1 more source