Results 41 to 50 of about 258,864 (309)

A Framework to Ensure Patient Partners Have Equal and Contributing Voices Throughout the Research Program Evaluation Process

open access: yesCanadian Journal of Kidney Health and Disease, 2020
Purpose of program: Traditionally, peer review was a closed process conducted only by individuals working in the research field. To establish a more integrated and patient-centered approach, one of Canada’s largest kidney research networks (Can-SOLVE CKD)
David R. Hillier   +12 more
doaj   +1 more source

Correlation of diuretic therapy toward clinicaloutcomeof patients suffering from chronic kidney disease hospitalized in RSUP DR. M. Djamil Padang [PDF]

open access: yesPharmaciana, 2018
Kidney is one of the most important organs of the human body. The goal of diuretic therapy is to reduce edema in patients with impaired renal function. The therapy of diuretic is very important, because the therapy is effective to control of the volume ...
Fathnur Sani K   +2 more
doaj   +1 more source

Mechanisms of Anemia in CKD [PDF]

open access: yesJournal of the American Society of Nephrology, 2012
Anemia is a common feature of CKD associated with poor outcomes. The current management of patients with anemia in CKD is controversial, with recent clinical trials demonstrating increased morbidity and mortality related to erythropoiesis stimulating agents. Here, we examine recent insights into the molecular mechanisms underlying anemia of CKD.
Jodie L, Babitt, Herbert Y, Lin
openaire   +2 more sources

Salvianolic Acid C Inhibits the Epithelial-Mesenchymal Transition and Ameliorates Renal Tubulointerstitial Fibrosis

open access: yesFrontiers in Bioscience-Landmark, 2023
Background: Salvianolic acid C (SAC) is a natural compound derived from Salvia miltiorrhiza that can protect against renal diseases. The aims of this work were to explore the effect of SAC on kidney tubulointerstitial fibrosis and study the associated ...
Ming Wu   +4 more
doaj   +1 more source

Insulin Resistance in CKD [PDF]

open access: yesClinical Journal of the American Society of Nephrology, 2014
Insulin resistance is typically defined as decreased biologic action of insulin at its target organs ( e.g., liver, skeletal muscles) for any given blood concentration of insulin. Clinically it usually presents with hyperinsulinemia, glucose intolerance, hyperglycemia, and dyslipidemia ...
Sarah, Leyking, Danilo, Fliser
openaire   +2 more sources

CKD-induced mitochondrial damage.

open access: yes, 2018
(A) Relative expression of CytB as a marker for total mitochondrial content, relative to 18S. (B) Citrate synthase activity as an indicator for intact mitochondrial content.
Lena Cohen (4012094)   +7 more
core   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo   +5 more
wiley   +1 more source

Identification of driver genes in renal stress condition using network clustering approach [PDF]

open access: yesNetwork Biology, 2021
Chronic kidney disease (CKD) is a non-contagious, ageing-related and covert disease. It is a (chronic) disease of the kidneys leading to renal failure, huge public health problem worldwide and common comorbidity with type 2 diabetes mellitus (T2DM).
Mohd Murshad Ahmed   +2 more
doaj  

Kidney disease management in UK primary care: guidelines, incentives and Information Technology [PDF]

open access: yes, 2007
The last few years have seen new developments to understand and tackle the significant public health issue posed by chronic kidney disease (CKD). Established renal disease currently consumes 2% of the UK National Health Service budget and predictions are
O'Donoghue, Donal J.   +7 more
core   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa   +7 more
wiley   +1 more source

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