Results 41 to 50 of about 258,864 (309)
Purpose of program: Traditionally, peer review was a closed process conducted only by individuals working in the research field. To establish a more integrated and patient-centered approach, one of Canada’s largest kidney research networks (Can-SOLVE CKD)
David R. Hillier +12 more
doaj +1 more source
Correlation of diuretic therapy toward clinicaloutcomeof patients suffering from chronic kidney disease hospitalized in RSUP DR. M. Djamil Padang [PDF]
Kidney is one of the most important organs of the human body. The goal of diuretic therapy is to reduce edema in patients with impaired renal function. The therapy of diuretic is very important, because the therapy is effective to control of the volume ...
Fathnur Sani K +2 more
doaj +1 more source
Mechanisms of Anemia in CKD [PDF]
Anemia is a common feature of CKD associated with poor outcomes. The current management of patients with anemia in CKD is controversial, with recent clinical trials demonstrating increased morbidity and mortality related to erythropoiesis stimulating agents. Here, we examine recent insights into the molecular mechanisms underlying anemia of CKD.
Jodie L, Babitt, Herbert Y, Lin
openaire +2 more sources
Background: Salvianolic acid C (SAC) is a natural compound derived from Salvia miltiorrhiza that can protect against renal diseases. The aims of this work were to explore the effect of SAC on kidney tubulointerstitial fibrosis and study the associated ...
Ming Wu +4 more
doaj +1 more source
Insulin Resistance in CKD [PDF]
Insulin resistance is typically defined as decreased biologic action of insulin at its target organs ( e.g., liver, skeletal muscles) for any given blood concentration of insulin. Clinically it usually presents with hyperinsulinemia, glucose intolerance, hyperglycemia, and dyslipidemia ...
Sarah, Leyking, Danilo, Fliser
openaire +2 more sources
CKD-induced mitochondrial damage.
(A) Relative expression of CytB as a marker for total mitochondrial content, relative to 18S. (B) Citrate synthase activity as an indicator for intact mitochondrial content.
Lena Cohen (4012094) +7 more
core +1 more source
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source
Identification of driver genes in renal stress condition using network clustering approach [PDF]
Chronic kidney disease (CKD) is a non-contagious, ageing-related and covert disease. It is a (chronic) disease of the kidneys leading to renal failure, huge public health problem worldwide and common comorbidity with type 2 diabetes mellitus (T2DM).
Mohd Murshad Ahmed +2 more
doaj
Kidney disease management in UK primary care: guidelines, incentives and Information Technology [PDF]
The last few years have seen new developments to understand and tackle the significant public health issue posed by chronic kidney disease (CKD). Established renal disease currently consumes 2% of the UK National Health Service budget and predictions are
O'Donoghue, Donal J. +7 more
core +1 more source
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa +7 more
wiley +1 more source

