Whole‐Body Pattern of Muscle Degeneration and Progression in Sarcoglycanopathies
ABSTRACT Objective To characterize whole‐body intramuscular fat distribution pattern in patients with sarcoglycanopathies and explore correlations with disease severity, duration and age at onset. Methods Retrospective, cross‐sectional, multicentric study enrolling patients with variants in one of the four sarcoglycan genes who underwent whole‐body ...
Laura Costa‐Comellas +39 more
wiley +1 more source
A clínica do luto e seus critérios diagnósticos: possíveis contribuições de Tatossian
Resumo O Manual diagnóstico e estatístico de transtornos mentais (DSM-5) avulta a discussão do problema da diferenciação entre luto normal e complicado. Tendo por fundamento a obra de Arthur Tatossian e uma perspectiva fenomenológica do luto, temos como ...
Luís Henrique Fuck Michel +1 more
doaj +1 more source
Chronic Trypanosoma cruzi infection potentiates adipose tissue macrophage polarization toward an anti-inflammatory M2 phenotype and contributes to diabetes progression in a diet-induced obesity model [PDF]
Chronic obesity and Chagas disease (caused by the protozoan Trypanosoma cruzi) represent serious public health concerns. The interrelation between parasite infection, adipose tissue, immune system and metabolism in an obesogenic context, has not been ...
Andrada, Marta Cecilia +8 more
core +4 more sources
ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio +8 more
wiley +1 more source
Stillbirth rates in 20 countries of Latin America: an ecological study [PDF]
Objective: To describe country-level stillbirth rates and their change over time in Latin America, and to measure the association of stillbirth rates with socio-economic and health coverage indicators in the region. Design: Ecological study.
Althabe, Fernando +5 more
core +1 more source
Objective This study assessed sarilumab in treating patients with polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods This phase 2b, open‐label study (NCT02776735) consisted of three sequential parts (each with a core‐treatment and extension phase).
Fabrizio De Benedetti +19 more
wiley +1 more source
Evolución clínica y pronóstico en adolescentes obesos al oeste de La Habana
Introducción: la obesidad en niños continúa ascendiendo relacionándola con la aparición de lesiones ateroescleróticas en adultos jóvenes obesos.
Ernesto Canciano Chirino +3 more
doaj +2 more sources
Guía de práctica clínica para el manejo del cáncer de pulmón de células pequeñas: enfermedad extensa
Antecedentes: El cáncer de células pequeñas (CPCP) representa el 13-15% del total de neoplasias primarias de pulmón. Se caracteriza por su rapidez en la tasa de crecimiento y en el desarrollo de metástasis a distancia. Objetivos: Orientar y estandarizar el tratamiento del CPCP enfermedad extensa en México basado en evidencia clínica nacional e ...
Luis A. Cabrera-Miranda +29 more
openaire +2 more sources
Circulating Tumor Cells in Multiple Myeloma: From Peripheral Clues to Central Insights
CTC offer a minimally invasive widow into systemic myeloma biology, overcoming the sampling bias of bone marrow biopsies. Their prognostic value at diagnosis, potential role in MRD monitoring, and ability to capture clonal evolution highlight them as actionable biomarkers for future precision medicine.
Benjamin Podvin +3 more
wiley +1 more source
Ética y clínica: Entre el deseo y el bien-decir
El presente texto busca dar cuenta de la ética que se pone en juego en la clínica psicoanalítica, evidenciando que se trata de una ética del deseo y no del deber, esto quiere decir que involucra la singularidad del sujeto y por lo tanto se trata de una ...
Fabian Becerra Fuquen
doaj +1 more source

