Results 131 to 140 of about 1,370,885 (248)

Population genetics of the protected insect "Graellsia isabellae" (Lepidoptera: Saturniidae) [PDF]

open access: yes, 2015
[Resumen] Graellsia isabellae (Lepidoptera: Saturniidae) es un insecto de hábitos nocturnos que se encuentra en pinares de montaña de España (Pirineos occidentales y orientales, Sistema Central, Montañas Béticas y Sistema ...
González-López, Jorge
core  

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui   +6 more
wiley   +1 more source

Funcionalització d'o-carborans iodats per obtenir estructures dendrimèriques útils en aplicacions mèdiques [PDF]

open access: yes, 2011
L'1,2-dicarba-closo-dodecaborà, l'o-carborà, és un clúster icosaèdric format per deu vèrtexs de bora–hidrogen i dos vèrtexs de carboni–hidrogen en posició adjacent.
Pepiol, Ariadna   +3 more
core  

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

The new complexity: new dynamics in clusters and districts [PDF]

open access: yes
Recently, service clusters have been identified, such as in the case of the logistics and transportation cluster in the Basque Country (e.g. transportation of people and ware, intelligent transport services, etc.) or that of port activities (warehousing ...
M Davide Parrilli
core  

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

The exporting propensity of the social andalusian economy: analysis cluster [PDF]

open access: yes, 2017
Este trabajo tuvo como objetivo determinar los factores internos (tamaño, presupuesto de innovación, ventas en el exterior, incremento de la exportación y comercio electrónico) y los factores externos (sector económico) que condicionan la propensión ...
Espasandin Bustelo, Francisco   +2 more
core  

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Estudi i implementació d'un sistema de computació en núvol [PDF]

open access: yes, 2013
En aquest projecte s'ha avaluat la infraestructura de computació en núvol. Concretament, s'ha estudiat el seu funcionament i les diverses implementacions que existeixen, intentant discernir si aquest tipus d'infraestructura informàtica aporta alguna ...
Guerrero Vilarrasa, Carles   +2 more
core  

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