Results 131 to 140 of about 1,390,749 (248)
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Funcionalització d'o-carborans iodats per obtenir estructures dendrimèriques útils en aplicacions mèdiques [PDF]
, 2011 L'1,2-dicarba-closo-dodecaborà, l'o-carborà, és un clúster icosaèdric format per deu vèrtexs de borahidrogen i dos vèrtexs de carbonihidrogen en posició adjacent.
Pepiol, Ariadna +3 more
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Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Los micro-clusters turísticos ¿una herramienta para el desarrollo turístico en zonas rurales deprimidas? [PDF]
, 2009 Este trabajo explora las posibilidades que ofrecen las redes y el enfoque de los microclusters para el desarrollo turístico en comunidades rurales desfavorecidas, mediante la revisión y reflexión de la bibliografía específica.
Sáez Cala, Antonia
core +4 more sources
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
150 investigadors participen a la primera trobada científica del BNC-b [PDF]
, 2011 Un total de 150 investigadors de l'àmbit de la nanotecnologia i la nanociència de la UAB i del seu entorn que pertanyen a centres del clúster de nanotecnologia BNC-b (Barcelona Nanotecnology Cluster -Bellaterra) es van reunir el passat 14 de juliol per ...
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Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Estudi i implementació d'un sistema de computació en núvol [PDF]
, 2013 En aquest projecte s'ha avaluat la infraestructura de computació en núvol. Concretament, s'ha estudiat el seu funcionament i les diverses implementacions que existeixen, intentant discernir si aquest tipus d'infraestructura informàtica aporta alguna ...
Guerrero Vilarrasa, Carles +2 more
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