Results 111 to 120 of about 1,987,455 (278)
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Las políticas de desarrollo de clústeres han llegado a fomentar la cooperación entre empresas y mejorar la competitividad regional en general. En la mayoría de los países latinoamericanos no existe una política pública en la materia como tal, por lo ...
Silvia Paola Leitón Elizondo +1 more
doaj +1 more source
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Estimación de pautas de asociación y patrones de distribución de edificaciones aisladas en espacios rurales mediante SIG y técnicas basadas en procesos puntuales. [PDF]
En este trabajo se propone un método basado en las técnicas de estadística espacial y SIG para identificar la existencia de patrones geográficos de distribución y asociación de la vivienda rural.
Galacho-Jimenez, Federico Benjamin
core
Difusión de conocimientos e innovación en el clúster electrónico de Córdoba : análisis de las firmas miembro de una asociación empresarial [PDF]
La teoría de Sistemas Nacionales de Innovación (SNI) considera que las empresas no innovan de manera aislada sino en interacción con otras firmas y con la infraestructura de conocimientos; a través del ARS es posible contrastar este postulado.
Bressan, Cecilia, Matta, Andrés
core +3 more sources
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Cultura y consumo de energía en el sector residencial de Montevideo, Uruguay [PDF]
La ponencia presenta los resultados del abordaje cualitativo para el estudio del consumo de energía exosomática en hogares de Montevideo, capital del Uruguay.
Taks, Javier
core
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source

