Results 151 to 160 of about 1,987,455 (278)

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

WRF, análisis de rendimiento en clústeres HPC

open access: yesMaskana, 2017
El modelo WRF (Weather Research and Forecasting) es un sistema de predicción numérica del clima de mesoescala, diseñado tanto para las operaciones de predicción como para la investigación atmosférica, con énfasis en la escalabilidad, la eficiencia y la ...
Brayme Guamán, Lizandro Solano
doaj  

Desarrollo de un sistema de análisis de imágenes usando información de redes sociales [PDF]

open access: yes, 2018
Las redes sociales se han convertido hoy en día en una de las mayores fuentes de información pública que existen. Dada la cantidad de usuarios que diariamente utilizan este tipo de plataformas (como Facebook, Twitter, o Instagram), hacen que estas sean ...
Gómez Aguirre, Santiago
core  

Semi-Supervised Learning

open access: yesEncyclopedia of Database Systems, 2019
Sugato Basu
semanticscholar   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

[Structural changes to the brain in drug-resistant juvenile myoclonic epilepsy]. [PDF]

open access: yesRev Neurol, 2022
Sánchez-Zapata P   +2 more
europepmc   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Comportamiento de la empresa criminal productora de cocaína en Antioquia, desde el análisis econométrico espacial [PDF]

open access: yes, 2016
El enfoque principal del presente estudio se basa en el análisis de la cadena productiva de cocaína en el Departamento de Antioquia (Colombia), particularmente en sus 125 municipios durante el periodo 2010-2015 -- Se utiliza el análisis econométrico e ...
Arias Cuéllar, Juan Carlos   +1 more
core  

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

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