LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
[Determinantes del puntaje PHQ 9 para síntomas depresivos mayores en trabajadores de la salud durante la pandemia de COVID-19 mediante técnicas de <i>machine learning</i>]. [PDF]
Luciano B +5 more
europepmc +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Escenarios de delincuencia juvenil en el ámbito urbano: una perspectiva situacional
A lo largo de las tres últimas décadas se ha incrementado de forma notable el estudio de las variables espaciales y contextuales asociadas a la delincuencia.
Alexander Trinidad +2 more
doaj
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
[Creation of Patient Profiles and a Screening Tool for Individuals with Pain]. [PDF]
Morcuende Campos A +4 more
europepmc +1 more source
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Stress grounded in experiences of racial discrimination: a cluster analysis among a racially diverse sample in Canada. [PDF]
Moshirian Farahi SMM, Cénat JM.
europepmc +1 more source
A Cluster-Randomized Trial to Test Sharing Histories as a Training Method for Community Health Workers in Peru. [PDF]
Altobelli LC +3 more
europepmc +1 more source
Los Microclusters Turísticos: ¿una herramienta para el desarrollo turistico en zonas rurales deprimidas. [PDF]
Este trabajo explora las posibilidades que ofrecen las redes y el enfoque de los microclusterspara el desarrollo turístico en comunidades rurales desfavorecidas, mediante la revisión y reflexión de la bibliografía específica.
Antonia Saez Cala
core

