Results 181 to 190 of about 1,987,455 (278)

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Spatial and temporal behavior of rocky mountain spotted fever in Sinaloa, Mexico: study period 2015-2023. [PDF]

Rev Peru Med Exp Salud Publica
Castellanos-Tamayo Á, Rivero-Perez N, Valladares-Carranza B, Rosenfel-Miranda C, Morales-Ubaldo Y, Aparicio-Burgos JE, Sosa-Gutiérrez CG, Zaragoza-Bastida A.   +7 more
europepmc   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Caracterización genómica de los mecanismos de adaptación de Pseudomonas aeruginosa en pacientes con bronquiectasias. [PDF]

Adv Lab Med
Santa AM, Gómez-Arbonés X, Pifarré Teixidó R, García-González M, Bellés Bellés A.   +4 more
europepmc   +1 more source

Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma

Molecular Oncology, EarlyView.
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga, María Luz Martinez‐Chantar, Carolina Conter   +2 more
wiley   +1 more source

[Cluster predictors of trajectories of leisure-time physical activity intensity in men and women from ELSA-Brasil]. [PDF]

Cad Saude Publica
Duque ALMDS, Paula DP, Pitanga FJG, Queiroz CO, Molina MDCB, Moreira AD, Moreira AD, Almeida MDCC, Matos SMA, Patrão AL, Fonseca MJMD, Griep RH.   +11 more
europepmc   +1 more source

[Approach to digital transformation in healthcare to reduce the digital divide]. [PDF]

Aten Primaria, 2023
Vidal-Alaball J, Alarcon Belmonte I, Panadés Zafra R, Escalé-Besa A, Acezat Oliva J, Saperas Perez C.   +5 more
europepmc   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Spatial scanning for the identification of risk areas for fetal death: an ecological study in Pernambuco. [PDF]

Rev Esc Enferm USP
Canuto IMB, Bonfim CVD, Silva APSC.
europepmc   +1 more source

Planck 2015 results: XXIII. The thermal Sunyaev-Zeldovich effect-cosmic infrared background correlation

, 2016
P. Ade, N. Aghanim, M. Arnaud, J. Aumont, C. Baccigalupi, A. Banday, A. Banday, R. B. Barreiro, J. G. Bartlett, J. G. Bartlett, N. Bartolo, N. Bartolo, E. Battaner, K. Benabed, A. Benoit-Lévy, A. Benoit-Lévy, J. Bernard, J. Bernard, M. Bersanelli, M. Bersanelli, P. Bielewicz, P. Bielewicz, J. Bock, A. Bonaldi, L. Bonavera, J. R. Bond, J. Borrill, J. Borrill, F. Bouchet, C. Burigana, C. Burigana, R. C. Butler, E. Calabrese, A. Catalano, A. Chamballu, A. Chamballu, A. Chamballu, H. Chiang, H. Chiang, P. Christensen, E. Churazov, E. Churazov, D. Clements, L. Colombo, L. Colombo, C. Combet, B. Comis, F. Couchot, A. Coulais, B. Crill, A. Curto, A. Curto, F. Cuttaia, L. Danese, R. Davies, R. J. Davis, P. Bernardis, A. Rosa, G. Zotti, G. Zotti, J. Delabrouille, C. Dickinson, J. M. Diego, H. Dole, H. Dole, S. Donzelli, O. Doré, M. Douspis, A. Ducout, A. Ducout, X. Dupac, G. Efstathiou, F. Elsner, F. Elsner, T. Ensslin, H. Eriksen, F. Finelli, I. Flores-Cacho, I. Flores-Cacho, O. Forni, O. Forni, M. Frailis, A. Fraisse, E. Franceschi, S. Galeotta, S. Galli, K. Ganga, R. Génova-Santos, R. Génova-Santos, M. Giard, M. Giard, Y. Giraud-Héraud, E. Gjerløw, J. González-Nuevo, J. González-Nuevo, K. Górski, K. Górski, A. Gregorio, A. Gregorio, A. Gruppuso, J. Gudmundsson, F. Hansen, D. Harrison, G. Helou, C. Hernández-Monteagudo, D. Herranz, S. Hildebrandt, E. Hivon, M. Hobson, A. Hornstrup, W. Hovest, K. Huffenberger, G. Hurier, A. Jaffe, T. Jaffe, T. Jaffe, W. Jones, E. Keihänen, R. Keskitalo, T. Kisner, R. Kneissl, R. Kneissl, J. Knoche, M. Kunz, M. Kunz, M. Kunz, H. Kurki-Suonio, G. Lagache, G. Lagache, J. Lamarre, M. Langer, A. Lasenby, M. Lattanzi, C. Lawrence, R. Leonardi, F. Levrier, P. Lilje, M. Linden-Vørnle, M. López-Caniego, M. López-Caniego, P. Lubin, J. Macías-Pérez, B. Maffei, G. Maggio, D. Maino, D. Maino, D. Mak, N. Mandolesi, N. Mandolesi, A. Mangilli, M. Maris, P. Martin, E. Martínez-González, S. Masi, S. Matarrese, S. Matarrese, A. Melchiorri, A. Mennella, A. Mennella, M. Migliaccio, S. Mitra, S. Mitra, M. Miville-Deschênes, M. Miville-Deschênes, A. Moneti, L. Montier, L. Montier, G. Morgante, D. Mortlock, D. Munshi, J. A. Murphy, F. Nati, P. Natoli, P. Natoli, P. Natoli, F. Noviello, D. Novikov, I. Novikov, I. Novikov, C. A. Oxborrow, F. Paci, L. Pagano, F. Pajot, D. Paoletti, B. Partridge, F. Pasian, T. Pearson, O. Perdereau, L. Perotto, V. Pettorino, F. Piacentini, M. Piat, E. Pierpaoli, S. Plaszczynski, E. Pointecouteau, E. Pointecouteau, G. Polenta, G. Polenta, N. Ponthieu, N. Ponthieu, G. Pratt, S. Prunet, J. Puget, J. Rachen, J. Rachen, M. Reinecke, M. Remazeilles, M. Remazeilles, M. Remazeilles, C. Renault, A. Renzi, I. Ristorcelli, I. Ristorcelli, G. Rocha, C. Rosset, M. Rossetti, M. Rossetti, G. Roudier, G. Roudier, G. Roudier, J. Rubiño-Martín, J. Rubiño-Martín, B. Rusholme, M. Sandri, D. Santos, M. Savelainen, G. Savini, D. Scott, L. Spencer, V. Stolyarov, V. Stolyarov, V. Stolyarov, R. Stompor, R. Sunyaev, R. Sunyaev, D. Sutton, A.-S. Suur-Uski, J. Sygnet, J. Tauber, L. Terenzi, L. Toffolatti, L. Toffolatti, L. Toffolatti, M. Tomasi, M. Tomasi, M. Tristram, M. Tucci, G. Umana, L. Valenziano, J. Valiviita, B. Tent, P. Vielva, F. Villa, L. Wade, B. Wandelt, B. Wandelt, I. Wehus, N. Welikala, D. Yvon, A. Zacchei, A. Zonca   +260 more
semanticscholar   +1 more source