Results 181 to 190 of about 769,510 (265)

Correction. [PDF]

open access: yesGut Microbes
europepmc   +1 more source

A Personalized Haplotype‐Resolved Near‐Gapless Genome Framework for Somatic Variant Discovery in Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
A patient‐specific, haplotype‐resolved genome framework improves detection and interpretation of somatic variants in hepatocellular carcinoma. Using multi‐platform sequencing, the personalized assembly resolves complex regions including centromeres and MHC/HLA loci, enhances structural variant discovery, and links regulatory alterations to allele ...
Jiazheng Lin   +17 more
wiley   +1 more source

Deciphering Anti‐Cancer Drug Efficacy Through Nanomechanical Vibrations in Living Gastric Cancer Organoids

open access: yesAdvanced Science, EarlyView.
This study developed an efficacy assessment platform that integrates patient‐derived gastric cancer organoids, atomic force microscopy (AFM)‐based nanomechanical vibration detection, deep learning analysis, and organoid mechanical modeling. It detects picomolar drug effects within 0.1 s signal, achieves 97% classification accuracy, and offers non ...
Ting Zhang   +10 more
wiley   +1 more source

Long-term prophylaxis in hereditary angioedema: Real-world treatment patterns and healthcare resource utilization. [PDF]

open access: yesWorld Allergy Organ J
Tachdjian R   +7 more
europepmc   +1 more source

Engineering Slow‐Carrier Interfacial Recombination Enables Tailored Spectral Response

open access: yesAdvanced Science, EarlyView.
This work demonstrates that weak‐drift slow carriers are preferentially captured at generic semiconductor surfaces/interfaces and recombine. This process is manipulated to achieve tailored spectral response. A tens of µm‐wide depletion region is created to observe surface collection rates for photocarriers generated at different positions.
Yibo Zhang   +5 more
wiley   +1 more source

Dimple‐Encoded Reprogrammable Origami

open access: yesAdvanced Science, EarlyView.
Local snap‐through of bistable dimples turns flat elastic sheets into reprogrammable origami structures. Interaction‐guided dimple arrays act as angle‐programmable hinge bands, enabling one sheet to morph into distinct polygonal and three‐dimensional configurations while retaining stable shapes for deployable and protective functions.
Qun Zhang   +6 more
wiley   +1 more source

Systematic Multi‐Level Analyses Decode the Arthritis‐Neurodegeneration Axis With In Vivo Validation

open access: yesAdvanced Science, EarlyView.
Arthritis and neurodegeneration are usually studied as separate disorders, but this study connects them through population evidence, genetic inference, transcriptomic mapping, and mouse models. It highlights RNF40 as a context‐dependent joint‐brain candidate, induced in inflammatory joints yet functionally linked to dopamine‐neuron vulnerability ...
Jinwen Wang   +7 more
wiley   +1 more source

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