Results 31 to 40 of about 1,284,015 (301)

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Cerebrovascular CTA radiomics for objective collateral grading in acute ischemic stroke

European Radiology Experimental
Objective Collateral circulation is a key determinant of functional outcome after large vessel occlusion (LVO) and informs thrombectomy decisions. However, collateral grading is rater-dependent and error-prone.
Dimitrios Rallios, Adam Hilbert, Charles Majoie, Wim Van H. van Zwam, Aad van der Lugt, Martin Bendszus, Susanne Bonekamp, Peter Vajkoczy, Orhun U. Aydin, Dietmar Frey   +9 more
doaj   +1 more source

Management and reduction of fraud by analysis of the insurer’s internal and external vulnerabilities and contributions [PDF]

Revista de Studii Financiare, 2021
Fraud is a dynamic phenomenon: when the industry discovers a „scam” – a specific pattern of fraud – and sets up barriers to prevent it from recurring, another scam takes place – a new pattern is developed by fraudsters.
Mihai Ovidiu Vădean
doaj  

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

External validation of AI-based scoring systems in the ICU: a systematic review and meta-analysis

BMC Medical Informatics and Decision Making
Background Machine learning (ML) is increasingly used to predict clinical deterioration in intensive care unit (ICU) patients through scoring systems.
Patrick Rockenschaub, Ela Marie Akay, Benjamin Gregory Carlisle, Adam Hilbert, Joshua Wendland, Falk Meyer-Eschenbach, Anatol-Fiete Näher, Dietmar Frey, Vince Istvan Madai   +8 more
doaj   +1 more source

Health Insurance: Effects and Awareness

Journal of the College of Community Physicians, 2013
DOI: http://dx.doi.org/10.4038/jccpsl.v18i1.6078 Journal of the College of Community Physicians of Sri Lanka Vol.18(1) June 2013 30 ...
Bhavesh Desai, Ravi Desai, Gaurang Algotar, Kanan T Desai, RK Bansal   +4 more
doaj   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

MEANING OF THE TERMS AMNESTY AND PARDON IN THE MACEDONIAN CRIMINAL LAW [PDF]

Journal of Process Management and New Technologies, 2017
From ancient times and on, the amnesty and the pardon represent an act of grace, term of highest grace that provides the necessary safety valve of justice.
Nada Simjanoska
doaj   +1 more source

La nòva cançon occitana e la societat miègjornala

Lengas, 2022
From the end of the 1960s onwards, the Nouvelle chanson occitane (NCO) became an important vehicle for the transmission of occitanist themes in southern society. In return, it also echoed the social struggles that were being waged in the Oc region during
Yan Lespoux
doaj   +1 more source

The representative claim

, 2010
In an era of disaffection from traditional political institutions and the rise of transnational politics, the need to rethink political representation – who speaks for whom and with what authority – has taken on a new and practical urgency.
Saward, Michael
core   +1 more source